POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGJ_A_1PQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	6 / 9	TRP A 105 GLY A 149 GLY A 150 MET A 154 ASN A 161 GLU A 193	FAD  A 232 ( 4.3A) FAD  A 232 (-3.6A) FAD  A 232 (-3.6A) None None FAD  A 232 ( 3.1A)	0.15A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1bnl	COLLAGEN XVIII (Homo sapiens)	4 / 8	ILE A 100 PHE A  49 TRP A  83 GLY A  92	None	0.77A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	1zvd	SMAD UBIQUITINATION REGULATORY FACTOR 2 (Homo sapiens)	4 / 8	PHE A 504 ILE A 626 PHE A 508 GLY A 487	None	1.01A	20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2f9q	CYTOCHROME P450 2D6 (Homo sapiens)	5 / 8	PHE A 420 ILE A 360 PHE A 433 TRP A 409 GLY A 367	None	1.22A	19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2k1m	MYOSIN-BINDING PROTEIN C, CARDIAC-TYPE (Homo sapiens)	4 / 8	PHE A  28 ILE A  48 PHE A  89 GLY A  76	None	1.01A	21.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3te7	RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE] (Homo sapiens)	4 / 8	TRP A 105 GLY A 149 ASN A 161 GLU A 193	FAD  A 232 ( 4.3A) FAD  A 232 (-3.6A) None FAD  A 232 ( 3.1A)	0.09A	98.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3v4p	INTEGRIN ALPHA-4 (Homo sapiens)	4 / 8	GLN A 230 GLY A 225 ASN A 341 GLU A 234	None	1.01A	17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4ky9	BAND 3 ANION TRANSPORT PROTEIN (Homo sapiens)	4 / 8	GLN A 191 ILE A 276 GLY A 232 GLU A  63	None	0.97A	22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5bwa	ORNITHINE DECARBOXYLASE (Homo sapiens)	4 / 8	GLN A 341 ILE A  28 GLY A 378 ASN A 319	None	0.97A	19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5f0p	SORTING NEXIN-3 (Homo sapiens)	4 / 8	GLN C 100 ILE C 109 GLY C  94 GLU C  75	SO4  C 202 (-3.3A) SO4  C 202 (-4.4A) None None	1.02A	20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5nge	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 (Homo sapiens)	4 / 8	PHE A 409 ILE A 419 GLY A 458 ASN A 512	8WK  A 601 (-3.8A) None None None	0.95A	22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5nug	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 8	ILE A4294 GLY A4322 ASN A4325 GLU A4637	None	0.96A	4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGJ_A_1PQA304_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	5yq5	OSTEOMODULIN (Homo sapiens)	4 / 8	PHE A 296 ILE A 272 GLY A 288 ASN A 340	None	0.95A	undetectable