POTENTIAL TARGETS FROM HUMAN (RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES)1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.49A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 ALA A 194 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.59A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.74A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.45A	73.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3w1g	DNA LIGASE 4 (Homo sapiens)	5 / 12	SER A 63 TRP A 46 THR A 144 ALA A 67 ASN A 149	None	1.39A	20.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 ALA A 194 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None IXO A 501 (-3.5A) IXO A 501 (-4.6A)	1.25A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 ALA A 194 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None IXO A 501 (-3.5A) 2CU A 502 ( 3.9A)	0.90A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.28A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	0.87A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 194 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.91A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.16A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 ALA A 194 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.5A) IXO A 501 (-4.6A)	1.12A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 ALA A 194 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.5A) 2CU A 502 ( 3.9A)	0.85A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) IXO A 501 (-4.6A)	1.06A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) 2CU A 502 ( 3.9A)	0.74A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 TRP A 400 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) IXO A 501 (-4.6A) IXO A 501 (-3.5A)	1.17A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.98A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 400 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	1.20A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.06A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 194 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.93A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.22A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 TRP A 400 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	1.20A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.04A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.28A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 THR A 187 TRP A 400 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A) IXO A 501 (-3.5A)	1.25A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 THR A 187 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.02A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	TYR A 104 SER A 107 ASN A 108 TRP A 155 TYR A 426	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) 2CU A 502 ( 3.9A)	1.19A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 105 TYR A 106 SER A 109 TRP A 157 THR A 189 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.58A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.22A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 112 TYR A 113 SER A 116 ASN A 117 TRP A 164 THR A 196 ALA A 203 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) OLC A1208 ( 3.6A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.62A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 112 TYR A 113 THR A 199 TRP A 413 ASN A 417 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A)	1.41A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 113 THR A 199 TRP A 413 TYR A 416 CYH A 442	0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-3.6A)	1.46A	66.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1upr	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 (Homo sapiens)	5 / 12	ASP A1065 TRP A1072 THR A1122 THR A1120 ALA A1134	4IP A2154 (-3.7A) None None None None	1.36A	13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2iy0	RAN GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 12	ASP C 495 THR C 463 THR C 461 ALA C 472 TYR C 550	None	1.38A	16.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.40A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.75A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.29A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 SER A 107 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.38A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 SER A 107 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.06A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.24A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 THR A 187 THR A 190 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.93A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 194 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.97A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.27A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.97A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.20A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.38A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 THR A 190 ALA A 194 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.93A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 THR A 190 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.21A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 THR A 190 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.81A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	1.09A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 TRP A 155 THR A 187 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.32A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 TRP A 155 THR A 187 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	0.91A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	10 / 12	ASP A 105 TYR A 106 SER A 109 THR A 189 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.4A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.59A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.22A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 105 TYR A 106 TRP A 157 THR A 189 THR A 192 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.45A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 112 TYR A 113 SER A 116 THR A 196 THR A 199 ALA A 203 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.64A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 112 TYR A 113 THR A 196 TRP A 413 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.46A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 112 TYR A 113 TRP A 164 THR A 196 THR A 199 ALA A 203 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.51A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 113 THR A 196 ALA A 200 TYR A 439 CYH A 442	0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.30A	66.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1jdp	ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR (Homo sapiens)	3 / 3	ASN A 243 LEU A 146 PHE A 241	None	0.80A	22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1jeq	KU70 (Homo sapiens)	3 / 3	ASN A 171 LEU A 143 PHE A 169	None	0.81A	22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1o5e	SERINE PROTEASE HEPSIN (Homo sapiens)	3 / 3	ASN L 37 LEU L 86 PHE L 100	None	0.79A	13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1p6s	RAC-BETA SERINE/THREONINE PROTEIN KINASE (Homo sapiens)	3 / 3	ASN A 53 LEU A 78 PHE A 88	None	0.37A	13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1yvl	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA (Homo sapiens)	3 / 3	ASN A 520 LEU A 590 PHE A 581	None	0.81A	20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1zv6	EPB49 PROTEIN (Homo sapiens)	3 / 3	ASN A 23 LEU A 29 PHE A 76	None	0.81A	10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1zv6	EPB49 PROTEIN (Homo sapiens)	3 / 3	ASN A 23 LEU A 42 PHE A 76	None	0.76A	10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2eu9	DUAL SPECIFICITY PROTEIN KINASE CLK3 (Homo sapiens)	3 / 3	ASN A 242 LEU A 267 PHE A 246	None	0.82A	19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2f8a	GLUTATHIONE PEROXIDASE 1 (Homo sapiens)	3 / 3	ASN A 87 LEU A 94 PHE A 110	None	0.78A	18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2fw2	TESTIS-SPECIFIC CHROMODOMAIN PROTEIN Y 2 (Homo sapiens)	3 / 3	ASN A 27 LEU A 119 PHE A 260	None	0.82A	20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2i3y	EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE (Homo sapiens)	3 / 3	ASN A 112 LEU A 119 PHE A 135	None	0.71A	19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2jii	SERINE/THREONINE-PRO TEIN KINASE VRK3 MOLECULE: VACCINIA RELATED KINASE 3 (Homo sapiens)	3 / 3	ASN A 311 LEU A 294 PHE A 356	None	0.70A	21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2jxc	EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15 STONIN-2 (Homo sapiens)	3 / 3	ASN B 329 LEU A 165 PHE B 334	None	0.82A	6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2kjh	UBIQUITIN/ISG15-CONJ UGATING ENZYME E2 L6 (Homo sapiens)	3 / 3	ASN A 112 LEU A 86 PHE A 50	None	0.76A	16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2lav	VACCINIA-RELATED KINASE 1 (Homo sapiens)	3 / 3	ASN A 182 LEU A 165 PHE A 227	None	0.82A	19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2n7l	TROPONIN C/TROPONIN I CHIMERA (Homo sapiens)	3 / 3	ASN C 18 LEU C 111 PHE C 20	None	0.81A	13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2r37	GLUTATHIONE PEROXIDASE 3 (Homo sapiens)	3 / 3	ASN A 112 LEU A 119 PHE A 135	None	0.73A	18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2rsv	SERINE/THREONINE-PRO TEIN KINASE VRK1 (Homo sapiens)	3 / 3	ASN A 182 LEU A 165 PHE A 227	None	0.64A	19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2v5n	CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR (Homo sapiens)	3 / 3	ASN A1743 LEU A1663 PHE A1787	None	0.77A	19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2wgh	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE LARGE SUBUNIT (Homo sapiens)	3 / 3	ASN A 528 LEU A 466 PHE A 701	None	0.68A	21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3cuq	VACUOLAR PROTEIN-SORTING-ASSO CIATED PROTEIN 25 (Homo sapiens)	3 / 3	ASN C 121 LEU C 130 PHE C 176	None	0.66A	17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3gkj	NIEMANN-PICK C1 PROTEIN (Homo sapiens)	3 / 3	ASN A 103 LEU A 173 PHE A 101	None	0.81A	17.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.75A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.85A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 ASN A 108 THR A 187 THR A 190 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-4.3A) None None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.93A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 ASN A 108 THR A 187 THR A 190 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-4.3A) None None IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.24A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 SER A 107 ASN A 108 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.01A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 SER A 107 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.41A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 SER A 107 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.10A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 THR A 187 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.50A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.31A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 THR A 187 THR A 190 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.03A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 THR A 190 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.4A) None IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	1.26A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 THR A 190 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None None IXO A 501 (-4.6A)	1.10A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 THR A 190 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.84A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.28A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	0.93A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-4.6A)	1.12A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.86A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.19A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	10 / 12	ASP A 105 TYR A 106 SER A 109 THR A 189 THR A 192 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.66A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.19A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	10 / 12	ASP A 105 TYR A 106 TRP A 157 THR A 189 THR A 192 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.54A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 112 TYR A 113 ASN A 117 TRP A 164 THR A 196 THR A 199 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 ( 3.6A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.55A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 112 TYR A 113 SER A 116 ASN A 117 THR A 196 THR A 199 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) OLC A1208 ( 3.6A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.67A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 112 TYR A 113 THR A 199 TRP A 413 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.39A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.9A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.62A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.76A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.48A	73.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 SER A 107 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.29A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 SER A 107 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.4A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.08A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.23A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 THR A 187 THR A 190 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.03A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 THR A 190 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.4A) None IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	1.29A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 THR A 190 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.95A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 ASN A 108 THR A 187 THR A 190 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) None None IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.15A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.23A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 ASN A 108 TRP A 155 THR A 187 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.98A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.96A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) IXO A 501 (-4.6A)	1.06A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 155 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-3.6A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.91A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ASN A 108 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-4.3A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.15A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.48A	44.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 105 TYR A 106 SER A 109 TRP A 157 THR A 189 THR A 192 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.61A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.22A	74.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 112 TYR A 113 SER A 116 ASN A 117 TRP A 164 THR A 196 THR A 199 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) OLC A1208 ( 3.6A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.57A	66.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4DAJ_D_0HKD2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 112 TYR A 113 THR A 196 TRP A 413 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.49A	66.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1by7	PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-2) (Homo sapiens)	5 / 12	ILE A 114 THR A 177 ALA A 201 ALA A 358 ASN A 200	None	1.48A	21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1d7w	MYELOPEROXIDASE (Homo sapiens)	5 / 12	ILE C 413 ASP C 142 ALA A 63 ALA A 61 ASN A 66	None	1.25A	22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2gdz	NAD+-DEPENDENT 15-HYDROXYPROSTAGLAN DIN DEHYDROGENASE (Homo sapiens)	5 / 12	SER A 123 THR A 162 ALA A 166 ALA A 168 ASN A 239	None	0.98A	20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3qr2	BASIGIN (Homo sapiens)	5 / 12	ILE A 60 TYR A 64 SER A 70 ALA A 2 ALA A 25	None	1.49A	13.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.49A	73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ILE A 72 ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 191 ALA A 194 TRP A 400 ASN A 404 TYR A 426 CYH A 429	None QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.91A	73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	7 / 12	ILE A 72 ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	None QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	73.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ILE A 72 TYR A 104 THR A 190 ALA A 194 TRP A 400 CYH A 429	None QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 ( 4.0A)	1.49A	73.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4fdd	TRANSPORTIN-1 (Homo sapiens)	5 / 12	ILE A 91 THR A 144 ALA A 148 ALA A 151 TRP A 126	None	1.16A	20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.17A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 191 ALA A 194 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.5A) 2CU A 502 ( 3.9A)	0.99A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 191 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.99A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 191 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.23A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	1.13A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ILE A 72 ASP A 103 TYR A 104 THR A 187 ALA A 191 ALA A 194 TYR A 426	None IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-3.5A) 2CU A 502 ( 3.9A)	0.98A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ILE A 72 ASP A 103 TYR A 104 THR A 187 ALA A 191 ASN A 404 TYR A 426 CYH A 429	None IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.89A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ILE A 72 ASP A 103 TYR A 104 THR A 187 ALA A 191 TRP A 400 ASN A 404	None IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.13A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ILE A 72 ASP A 103 TYR A 104 TRP A 155 THR A 187 TRP A 400	None IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.34A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ILE A 72 ASP A 103 TYR A 104 TRP A 155 THR A 187 TYR A 426	None IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A)	1.03A	45.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 105 TYR A 106 THR A 192 ALA A 196 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.28A	73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	11 / 12	ILE A 74 ASP A 105 TYR A 106 SER A 109 THR A 189 ALA A 193 ALA A 196 TRP A 378 ASN A 382 TYR A 404 CYH A 407	None 0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.64A	73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	8 / 12	ILE A 74 ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	None 0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.25A	73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	11 / 12	ILE A 74 ASP A 105 TYR A 106 TRP A 157 THR A 189 ALA A 193 ALA A 196 TRP A 378 ASN A 382 TYR A 404 CYH A 407	None 0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.55A	73.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 112 TYR A 113 THR A 199 ALA A 203 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.38A	67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ILE A 81 ASP A 112 TYR A 113 SER A 116 THR A 196 ALA A 200 ALA A 203 TRP A 413 ASN A 417 TYR A 439 CYH A 442	None 0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) P6G A1205 (-4.6A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.71A	67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	8 / 12	ILE A 81 ASP A 112 TYR A 113 THR A 199 TRP A 413 ASN A 417 TYR A 439 CYH A 442	None 0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.45A	67.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ILE A 81 ASP A 112 TYR A 113 TRP A 164 THR A 196 ALA A 200 ALA A 203 TRP A 413 ASN A 417 TYR A 439 CYH A 442	None 0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.64A	67.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5mfa	MYELOPEROXIDASE (Homo sapiens)	5 / 12	ILE A 579 ASP A 308 ALA A 229 ALA A 227 ASN A 232	None	1.24A	20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1bix	AP ENDONUCLEASE 1 (Homo sapiens)	4 / 4	ASN A 277 LEU A 305 PHE A 266 TYR A 269	None	1.38A	19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1r4n	AMYLOID BETA PRECURSOR PROTEIN-BINDING PROTEIN 1 (Homo sapiens)	4 / 4	ASN A 517 LEU A 398 PHE A 532 TYR A 161	None	1.29A	21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3a98	ENGULFMENT AND CELL MOTILITY PROTEIN 1 (Homo sapiens)	4 / 4	ASN B 653 LEU B 638 PHE B 562 TYR B 662	None	1.50A	18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3whd	C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER D (Homo sapiens)	4 / 4	ASN A 129 LEU A 143 PHE A 134 TYR A 96	None	1.42A	17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4giz	MALTOSE-BINDING PERIPLASMIC PROTEIN, UBIQUITIN LIGASE EA6P: CHIMERIC PROTEIN PROTEIN E6 (Alphapapillomavi rus 9; Escherichia coli; Homo sapiens)	4 / 4	ASN C 105 LEU A 379 PHE C 69 TYR C 32	None	1.49A	14.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	4 / 4	ASN A 117 LEU A 190 PHE A 204 TYR A 416	OLC A1208 ( 3.6A) P6G A1205 (-4.6A) None 0HK A1201 (-4.2A)	0.31A	67.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5j68	ASTROTACTIN-2 (Homo sapiens)	4 / 4	ASN A 751 LEU A 727 PHE A 756 TYR A 859	None	1.39A	21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5vhi	26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 (Homo sapiens)	4 / 4	ASN f 371 LEU f 391 PHE f 376 TYR f 751	None	1.11A	18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1upr	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 (Homo sapiens)	5 / 12	ASP A1065 TRP A1072 THR A1122 THR A1120 ALA A1134	4IP A2154 (-3.7A) None None None None	1.45A	14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2gdz	NAD+-DEPENDENT 15-HYDROXYPROSTAGLAN DIN DEHYDROGENASE (Homo sapiens)	5 / 12	SER A 123 THR A 162 ALA A 166 ALA A 168 ASN A 239	None	1.25A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2iy0	RAN GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 12	ASP C 495 THR C 463 THR C 461 ALA C 472 TYR C 550	None	1.29A	18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3gcw	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (Homo sapiens)	5 / 12	TYR A 648 SER A 487 THR A 623 ALA A 674 ALA A 637	None	1.41A	19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 107 TYR A 108 SER A 111 TRP A 158 ALA A 195	5EH A1200 ( 2.6A) D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) 5EH A1200 ( 4.4A) D7V A1201 ( 4.7A)	0.62A	49.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 108 SER A 111 TRP A 158 THR A 194 ALA A 195 TRP A 428	D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) 5EH A1200 ( 4.4A) D7V A1201 ( 4.6A) D7V A1201 ( 4.7A) 5EH A1200 ( 3.4A)	1.16A	49.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.79A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.23A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 190 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.43A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 TRP A 400 TYR A 403 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.47A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	9 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.95A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	9 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None None IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.13A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	9 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.87A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None IXO A 501 (-4.6A)	1.28A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.02A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.18A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.39A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.38A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 SER A 109 THR A 189 TRP A 378 ASN A 382 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.4A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.7A)	1.47A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 105 TYR A 106 SER A 109 TRP A 157 THR A 189 THR A 192 ALA A 193 ALA A 196 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.9A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.50A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 105 TYR A 106 THR A 189 ALA A 193 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.7A)	1.24A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.24A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 106 THR A 192 ALA A 196 TYR A 404 CYH A 407	0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.22A	67.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5ddb	MENIN (Homo sapiens)	5 / 12	TYR A 222 SER A 178 THR A 210 THR A 193 ALA A 194	None None None DMS A 612 ( 4.7A) None	1.47A	21.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 112 TYR A 113 ALA A 203 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.43A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 112 TYR A 113 SER A 116 TRP A 164 THR A 196 THR A 199 ALA A 200 ALA A 203 TRP A 413 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.44A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 112 TYR A 113 THR A 196 TRP A 413 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 (-4.3A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.43A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 112 TYR A 113 THR A 199 ALA A 203 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.44A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 113 THR A 196 ALA A 200 TYR A 439 CYH A 442	0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.25A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 113 TRP A 164 TRP A 413 TYR A 416 CYH A 442	0HK A1201 ( 3.2A) OLC A1208 ( 4.0A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-3.6A)	1.50A	75.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5iqp	14-3-3 PROTEIN THETA (Homo sapiens)	6 / 12	ASP A 154 SER A 156 THR A 190 THR A 194 ALA A 192 ALA A 195	None	1.46A	19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5nuv	AUTOPHAGY-RELATED PROTEIN 16-1 (Homo sapiens)	5 / 12	SER A 579 THR A 339 ALA A 327 ALA A 582 ASN A 326	None	1.49A	21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5vem	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 5 (Homo sapiens)	5 / 12	THR A 78 THR A 81 ALA A 120 ASN A 87 TYR A 307	None None None NAG A 507 (-2.7A) None	1.49A	20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1l9x	GAMMA-GLUTAMYL HYDROLASE (Homo sapiens)	3 / 3	ASN A 183 PHE A 189 TYR A 210	None	0.90A	20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1pk6	COMPLEMENT C1Q SUBCOMPONENT, B CHAIN PRECURSOR (Homo sapiens)	3 / 3	ASN B 124 PHE B 97 TYR B 141	None	0.88A	16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1x67	DREBRIN-LIKE PROTEIN (Homo sapiens)	3 / 3	ASN A 11 PHE A 114 TYR A 71	None	0.88A	17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2b92	INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ASN A 111 PHE A 116 TYR A 144	ASN A 111 ( 0.6A) PHE A 116 ( 1.3A) TYR A 144 ( 1.3A)	0.58A	21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	3 / 3	ASN A 108 PHE A 195 TYR A 403	QNB A1162 (-4.9A) QNB A1162 (-4.4A) QNB A1162 (-3.9A)	0.53A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	3 / 3	ASN A 117 PHE A 204 TYR A 416	OLC A1208 ( 3.6A) None 0HK A1201 (-4.2A)	0.11A	75.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	1q3x	MANNAN-BINDING LECTIN SERINE PROTEASE 2 (Homo sapiens)	5 / 12	SER A 628 THR A 466 THR A 467 ALA A 468 ALA A 469	GOL A 701 (-3.4A) None None None None	1.49A	21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2gdz	NAD+-DEPENDENT 15-HYDROXYPROSTAGLAN DIN DEHYDROGENASE (Homo sapiens)	5 / 12	SER A 123 THR A 162 ALA A 166 ALA A 168 ASN A 239	None	1.03A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3fo5	THIOESTERASE, ADIPOSE ASSOCIATED, ISOFORM BFIT2 (Homo sapiens)	5 / 12	TYR A 546 THR A 527 THR A 551 ALA A 550 TRP A 404	1PE A 2 (-4.0A) 1PE A 2 ( 3.8A) 1PE A 2 (-4.5A) GOL A 595 (-4.3A) None	1.24A	19.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 107 TYR A 108 SER A 111 ALA A 195 TRP A 428	5EH A1200 ( 2.6A) D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) D7V A1201 ( 4.7A) 5EH A1200 ( 3.4A)	1.43A	49.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 108 SER A 111 THR A 194 ALA A 195 TRP A 428	D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) D7V A1201 ( 4.6A) D7V A1201 ( 4.7A) 5EH A1200 ( 3.4A)	1.40A	49.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 108 SER A 111 THR A 194 ALA A 195 TYR A 431	D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) D7V A1201 ( 4.6A) D7V A1201 ( 4.7A) 5EH A1200 (-4.4A)	1.12A	49.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	0.52A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.25A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.73A	65.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 THR A 190 ALA A 191 ALA A 194 TRP A 400	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) IXO A 501 (-4.6A)	1.09A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ASP A 103 TYR A 104 SER A 107 THR A 190 ALA A 191 ALA A 194 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.88A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ASP A 103 TYR A 104 SER A 107 THR A 190 ALA A 191 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.14A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	9 / 12	ASP A 103 TYR A 104 SER A 107 THR A 190 ALA A 191 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.98A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.21A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 THR A 187 THR A 190 ALA A 191 ALA A 194 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None None IXO A 501 (-3.5A) IXO A 501 (-3.5A)	0.90A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ASP A 103 TYR A 104 THR A 187 THR A 190 ALA A 191 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	0.96A	49.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	THR A 187 THR A 190 ALA A 191 ALA A 193 TYR A 403	None None None None IXO A 501 (-3.8A)	1.38A	49.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	4n4w	CYTOCHROME B(562),SMOOTHENED HOMOLOG (Homo sapiens; Shigella flexneri)	5 / 12	THR A 248 THR A 251 ALA A 250 ALA A 254 TYR A 269	None	1.34A	19.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 105 TYR A 106 SER A 109 THR A 189 THR A 192 ALA A 193 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.9A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.47A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 105 TYR A 106 THR A 189 ALA A 193 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.7A)	1.30A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 105 TYR A 106 THR A 192 ALA A 196 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.27A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.19A	67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 112 TYR A 113 SER A 116 THR A 196 THR A 199 ALA A 200 ALA A 203 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) P6G A1205 (-4.6A) OLC A1208 (-4.4A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.48A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 112 TYR A 113 THR A 199 ALA A 203 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) OLC A1208 (-4.4A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.38A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 113 THR A 196 ALA A 200 TYR A 439 CYH A 442	0HK A1201 ( 3.2A) P6G A1205 (-4.6A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.27A	75.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5v57	SMOOTHENED HOMOLOG,FLAVODOXIN,S MOOTHENED HOMOLOG (Desulfovibrio vulgaris; Homo sapiens)	5 / 12	THR A 248 THR A 251 ALA A 250 ALA A 254 TYR A 269	None	1.28A	21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5vem	ECTONUCLEOTIDE PYROPHOSPHATASE/PHOS PHODIESTERASE FAMILY MEMBER 5 (Homo sapiens)	5 / 12	THR A 78 THR A 81 ALA A 120 ASN A 87 TYR A 307	None None None NAG A 507 (-2.7A) None	1.44A	20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3ray	PR DOMAIN-CONTAINING PROTEIN 11 (Homo sapiens)	4 / 4	ASN A 138 TRP A 139 LEU A 177 PHE A 115	None	1.36A	18.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	4 / 4	ASN A 117 TRP A 164 LEU A 190 PHE A 204	OLC A1208 ( 3.6A) OLC A1208 ( 4.0A) P6G A1205 (-4.6A) None	0.29A	75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 107 TYR A 108 SER A 111 TRP A 158 ALA A 195 TRP A 428	5EH A1200 ( 2.6A) D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) 5EH A1200 ( 4.4A) D7V A1201 ( 4.7A) 5EH A1200 ( 3.4A)	1.16A	55.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 ALA A 191 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	1.40A	68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 ALA A 191 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.74A	68.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 191 ALA A 194 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.79A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 ALA A 191 TRP A 400 ASN A 404 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-4.6A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	0.90A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 ALA A 194 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) IXO A 501 (-3.5A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.75A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 TRP A 400 TYR A 426	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) IXO A 501 (-4.6A) 2CU A 502 ( 3.9A)	0.93A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.36A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 ALA A 191 TRP A 400 TYR A 403 ASN A 404 TYR A 426	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A)	1.07A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 ALA A 191 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.90A	41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 112 TYR A 113 ALA A 203 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	1.37A	61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	11 / 12	ASP A 112 TYR A 113 SER A 116 TRP A 164 ALA A 200 ALA A 203 TRP A 413 TYR A 416 ASN A 417 TYR A 439 CYH A 442	0HK A1201 (-4.0A) 0HK A1201 ( 3.2A) 0HK A1201 (-3.3A) OLC A1208 ( 4.0A) 0HK A1201 ( 4.2A) 0HK A1201 (-3.6A) 0HK A1201 (-4.3A) 0HK A1201 (-4.2A) 0HK A1201 (-2.8A) 0HK A1201 (-3.6A) 0HK A1201 (-3.6A)	0.38A	61.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5dzz	DESMOPLAKIN (Homo sapiens)	5 / 12	TYR A2183 SER A2131 GLN A2128 ALA A2053 ALA A2054	None	1.41A	22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1ad9	IGG CTM01 FAB (LIGHT CHAIN) (Homo sapiens)	3 / 3	THR L 102 THR L 85 PHE L 83	None	0.80A	17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1cee	GTP-BINDING RHO-LIKE PROTEIN WISKOTT-ALDRICH SYNDROME PROTEIN WASP (Homo sapiens)	3 / 3	THR A 52 THR A 43 PHE B 15	None	0.82A	20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1hfs	STROMELYSIN-1 (Homo sapiens)	3 / 3	THR A 193 THR A 187 PHE A 196	None	0.89A	14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2d86	VAV-3 PROTEIN (Homo sapiens)	3 / 3	THR A 84 THR A 87 PHE A 93	None	0.86A	14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2f5a	PROTEIN (ANTIBODY 2F5 (LIGHT CHAIN)) (Homo sapiens)	3 / 3	THR L 102 THR L 85 PHE L 83	None	0.87A	16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2ybu	ACIDIC MAMMALIAN CHITINASE (Homo sapiens)	3 / 3	THR A 118 THR A 121 PHE A 126	None	0.71A	21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3t5o	COMPLEMENT COMPONENT C6 (Homo sapiens)	3 / 3	THR A 693 THR A 710 PHE A 715	None	0.74A	18.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	3 / 3	THR A 187 THR A 190 PHE A 195	QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.4A)	0.51A	68.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4f92	U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE (Homo sapiens)	3 / 3	THR B 583 THR B 565 PHE B 555	None	0.68A	14.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	3 / 3	THR A 187 THR A 190 PHE A 195	None	0.49A	41.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5ao5	C-TYPE MANNOSE RECEPTOR 2 (Homo sapiens)	3 / 3	THR A 216 THR A 188 PHE A 198	SO4 A1512 (-4.1A) SO4 A1512 ( 4.0A) None	0.64A	22.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5dsg	MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4 (Escherichia virus T4; Homo sapiens)	3 / 3	THR A 196 THR A 199 PHE A 204	P6G A1205 (-4.6A) OLC A1208 (-4.4A) None	0.42A	61.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5hzh	RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1,NPH1-1,RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (Avena sativa; Homo sapiens)	3 / 3	THR A 24 THR A 25 PHE A 28	None None GTP A 401 (-4.8A)	0.89A	20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5ikr	PROSTAGLANDIN G/H SYNTHASE 2 (Homo sapiens)	3 / 3	THR A 578 THR A 427 PHE A 198	None	0.85A	22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1upr	PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 (Homo sapiens)	5 / 12	ASP A1065 TRP A1072 THR A1122 THR A1120 ALA A1134	4IP A2154 (-3.7A) None None None None	1.47A	14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2iy0	RAN GTPASE-ACTIVATING PROTEIN 1 (Homo sapiens)	5 / 12	ASP C 495 THR C 463 THR C 461 ALA C 472 TYR C 550	None	1.26A	19.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 108 SER A 111 TRP A 158 THR A 194 TRP A 428	D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) 5EH A1200 ( 4.4A) D7V A1201 ( 4.6A) 5EH A1200 ( 3.4A)	1.22A	48.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 TRP A 400 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 ( 4.0A)	1.39A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	10 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 TRP A 400 TYR A 403 TYR A 426 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.91A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 CYH A 429	QNB A1162 (-3.1A) QNB A1162 (-4.0A) QNB A1162 (-4.8A) QNB A1162 (-3.9A) QNB A1162 ( 4.0A)	1.37A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 THR A 187 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.47A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.75A	76.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3w1g	DNA LIGASE 4 (Homo sapiens)	5 / 12	SER A 63 TRP A 46 THR A 144 ALA A 67 ASN A 149	None	1.43A	18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4htp	DNA LIGASE 4 (Homo sapiens)	5 / 12	SER A 63 TRP A 46 THR A 144 ALA A 67 ASN A 149	None	1.46A	20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 THR A 187 THR A 190 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.87A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	ASP A 103 TYR A 104 SER A 107 TRP A 155 THR A 187 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.01A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 THR A 187 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.30A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	ASP A 103 TYR A 104 TRP A 155 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.4A) IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.45A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 194 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.81A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.00A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.12A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	8 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.94A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 TRP A 400	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None IXO A 501 (-3.5A) IXO A 501 (-4.6A)	1.13A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None IXO A 501 (-3.5A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.93A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 105 TYR A 106 ALA A 193 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.37A	61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	12 / 12	ASP A 105 TYR A 106 SER A 109 TRP A 157 THR A 189 THR A 192 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.44A	61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	5 / 12	ASP A 105 TYR A 106 THR A 189 ALA A 193 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.4A) 0HK A 501 (-3.9A) 0HK A 501 (-3.7A)	1.34A	61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	7 / 12	ASP A 105 TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.0A) 0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.25A	61.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1a81	SYK KINASE (Homo sapiens)	3 / 3	ASN A 108 LEU A 29 PHE A 16	None	0.77A	18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1a81	SYK KINASE (Homo sapiens)	3 / 3	ASN A 189 LEU A 183 PHE A 192	None	0.73A	18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1mox	EPIDERMAL GROWTH FACTOR RECEPTOR (Homo sapiens)	3 / 3	ASN A 128 LEU A 14 PHE A 126	None	0.81A	20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1o5e	SERINE PROTEASE HEPSIN (Homo sapiens)	3 / 3	ASN L 37 LEU L 86 PHE L 100	None	0.73A	14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1p6s	RAC-BETA SERINE/THREONINE PROTEIN KINASE (Homo sapiens)	3 / 3	ASN A 53 LEU A 78 PHE A 88	None	0.74A	14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1u0n	PLATELET GLYCOPROTEIN IB (Homo sapiens)	3 / 3	ASN D 205 LEU D 220 PHE D 201	None	0.83A	21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1yvl	SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA/BETA (Homo sapiens)	3 / 3	ASN A 520 LEU A 590 PHE A 581	None	0.73A	19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1zv6	EPB49 PROTEIN (Homo sapiens)	3 / 3	ASN A 23 LEU A 42 PHE A 76	None	0.82A	11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ad9	POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ASN A 132 LEU A 89 PHE A 130	C B 149 ( 3.3A) U B 150 ( 4.2A) None	0.77A	13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2b3o	TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 6 (Homo sapiens)	3 / 3	ASN A 101 LEU A 18 PHE A 5	None	0.77A	20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2bkr	SENTRIN-SPECIFIC PROTEASE 8 (Homo sapiens)	3 / 3	ASN A 41 LEU A 205 PHE A 36	None	0.82A	20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2f8a	GLUTATHIONE PEROXIDASE 1 (Homo sapiens)	3 / 3	ASN A 87 LEU A 94 PHE A 110	None	0.78A	20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2i3y	EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE (Homo sapiens)	3 / 3	ASN A 112 LEU A 119 PHE A 135	None	0.75A	18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2lxi	RNA-BINDING PROTEIN 10 (Homo sapiens)	3 / 3	ASN A 2 LEU A 22 PHE A 48	None	0.75A	13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2r37	GLUTATHIONE PEROXIDASE 3 (Homo sapiens)	3 / 3	ASN A 112 LEU A 119 PHE A 135	None	0.76A	17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2v5n	CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR (Homo sapiens)	3 / 3	ASN A1743 LEU A1663 PHE A1787	None	0.68A	20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2w4k	DEATH-ASSOCIATED PROTEIN KINASE 1 (Homo sapiens)	3 / 3	ASN A 144 LEU A 68 PHE A 138	MG A1304 ( 4.2A) None None	0.77A	20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3dw8	SERINE/THREONINE-PRO TEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM (Homo sapiens)	3 / 3	ASN B 237 LEU B 313 PHE B 234	None	0.77A	20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2zfu	CEREBRAL PROTEIN 1 (Homo sapiens)	5 / 12	SER A 286 TRP A 291 LEU A 364 TYR A 280 ASN A 255	None None SAH A 900 (-4.9A) None None	1.35A	18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3hfw	PROTEIN ADP-RIBOSYLARGININE HYDROLASE (Homo sapiens)	5 / 12	TYR A 80 SER A 158 TRP A 118 LEU A 357 TYR A 205	None	1.42A	21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3rze	HISTAMINE H1 RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Homo sapiens)	5 / 12	TYR A 108 SER A 111 TRP A 158 THR A 194 TRP A 428	D7V A1201 ( 3.7A) 5EH A1200 ( 3.7A) 5EH A1200 ( 4.4A) D7V A1201 ( 4.6A) 5EH A1200 ( 3.4A)	1.21A	48.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 104 SER A 107 THR A 187 TRP A 400 ASN A 404 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.8A) QNB A1162 (-4.7A) QNB A1162 (-2.9A) QNB A1162 ( 4.0A)	1.48A	76.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3uon	HUMAN M2 MUSCARINIC ACETYLCHOLINE, RECEPTOR T4 LYSOZYME FUSION PROTEIN (Escherichia virus T4; Homo sapiens)	11 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 THR A 190 ALA A 194 TRP A 400 TYR A 403 ASN A 404 TYR A 426 CYH A 429	QNB A1162 (-4.0A) QNB A1162 (-3.4A) QNB A1162 (-4.2A) QNB A1162 (-4.8A) QNB A1162 (-4.3A) QNB A1162 ( 4.0A) QNB A1162 (-4.7A) QNB A1162 (-3.9A) QNB A1162 (-2.9A) QNB A1162 ( 4.2A) QNB A1162 ( 4.0A)	0.73A	76.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3w1g	DNA LIGASE 4 (Homo sapiens)	5 / 12	SER A 63 TRP A 46 THR A 144 ALA A 67 ASN A 149	None	1.42A	18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4htp	DNA LIGASE 4 (Homo sapiens)	5 / 12	SER A 63 TRP A 46 THR A 144 ALA A 67 ASN A 149	None	1.45A	20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 194 ASN A 404 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	0.77A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 ALA A 194 TRP A 400 ASN A 404	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.5A) IXO A 501 (-4.6A) IXO A 501 (-3.0A)	1.00A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 TRP A 400 TYR A 403 ASN A 404	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-4.6A) IXO A 501 (-3.8A) IXO A 501 (-3.0A)	1.11A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 187 THR A 190 TYR A 403 ASN A 404 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None None IXO A 501 (-3.8A) IXO A 501 (-3.0A) IXO A 501 (-3.5A)	0.91A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 190 ALA A 194 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.5A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.70A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	7 / 12	TYR A 104 SER A 107 THR A 190 TYR A 403 ASN A 404 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) None IXO A 501 (-3.8A) IXO A 501 (-3.0A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.87A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 ALA A 194 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) IXO A 501 (-3.5A) 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	0.74A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None IXO A 501 (-3.5A) IXO A 501 (-3.5A)	0.93A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	6 / 12	TYR A 104 SER A 107 TRP A 155 THR A 187 ALA A 194 TRP A 400	IXO A 501 (-3.7A) IXO A 501 (-3.4A) IXO A 501 (-3.6A) None IXO A 501 (-3.5A) IXO A 501 (-4.6A)	1.15A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	TYR A 104 THR A 187 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.7A) None None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.28A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	5 / 12	TYR A 104 TRP A 155 ALA A 191 TYR A 426 CYH A 429	IXO A 501 (-3.7A) IXO A 501 (-3.6A) None 2CU A 502 ( 3.9A) IXO A 501 (-3.5A)	1.44A	60.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	12 / 12	TYR A 106 SER A 109 TRP A 157 LEU A 183 THR A 189 THR A 192 ALA A 196 TRP A 378 TYR A 381 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.4A) 0HK A 501 (-3.1A) 0HK A 501 (-4.0A) None 0HK A 501 (-4.4A) 0HK A 501 (-4.0A) 0HK A 501 (-3.6A) 0HK A 501 (-4.4A) 0HK A 501 (-4.1A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	0.38A	61.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5cxv	MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1 (Escherichia virus T4; Homo sapiens)	6 / 12	TYR A 106 THR A 192 TRP A 378 ASN A 382 TYR A 404 CYH A 407	0HK A 501 (-3.4A) 0HK A 501 (-4.0A) 0HK A 501 (-4.4A) 0HK A 501 (-2.8A) 0HK A 501 (-3.6A) 0HK A 501 (-3.7A)	1.28A	61.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2jfe	CYTOSOLIC BETA-GLUCOSIDASE (Homo sapiens)	3 / 3	ASP X 407 ASN X 410 PHE X 304	None	0.72A	22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2y23	MYOMESIN (Homo sapiens)	3 / 3	ASP A1322 ASN A1327 PHE A1318	None	0.74A	21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3c6m	SPERMINE SYNTHASE (Homo sapiens)	3 / 3	ASP A 201 ASN A 160 PHE A 158	SPM A 501 ( 3.8A) None None	0.73A	20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3h1v	GLUCOKINASE (Homo sapiens)	3 / 3	ASP X 409 ASN X 231 PHE X 152	None GLC X 500 (-3.8A) None	0.78A	21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3pow	CALRETICULIN (Homo sapiens)	3 / 3	ASP A 309 ASN A 115 PHE A 113	None	0.80A	18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3rbs	MYOMESIN-1 (Homo sapiens)	3 / 3	ASP A1322 ASN A1327 PHE A1318	None	0.72A	16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4a14	KINESIN-LIKE PROTEIN KIF7 (Homo sapiens)	3 / 3	ASP A 135 ASN A 131 PHE A 79	None	0.79A	23.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4mqt	MUSCARINIC ACETYLCHOLINE RECEPTOR M2 (Homo sapiens)	3 / 3	ASP A 103 ASN A 108 PHE A 195	IXO A 501 (-3.4A) IXO A 501 (-4.3A) None	0.78A	60.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4rh7	GREEN FLUORESCENT PROTEIN/CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 (Homo sapiens; synthetic construct)	3 / 3	ASP A3684 ASN A3654 PHE A3661	None	0.74A	7.89