KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
1K4T_D_TTCD990 1k4t TTC

DB01030
(Topotecan)		 ;
Homo sapiens		 DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation		 5 GLU A 356
ARG A 364
LYS A 532
ASP A 533
THR A 718
 TTC D 990
1RR8_A_TTCA100 1rr8 TTC

DB01030
(Topotecan)		 ;
Homo sapiens		 DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation		 5 GLU C 356
ARG C 364
LYS C 532
ASP C 533
THR C 718
 TTC A 100
1RRJ_B_TTCB990 1rrj TTC

DB01030
(Topotecan)		 ;
Homo sapiens		 DNA TOPOISOMERASE I PF01028
(Topoisom_I)
PF02919
(Topoisom_I_N)
PF14370
(Topo_C_assoc)
no annotation		 5 GLU A 356
ARG A 364
LYS A 532
ASP A 533
THR A 718
 TTC B 990