KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
4BJC_A_RPBA2162 4bjc RPB

DB12332
(Rucaparib)		 Homo sapiens TANKYRASE-2 PF00644
(PARP)		 8 HIS A1031
GLY A1032
TYR A1060
ALA A1062
LYS A1067
SER A1068
TYR A1071
GLU A1138
 RPB A2162
4RV6_A_RPBA1103 4rv6 RPB

DB12332
(Rucaparib)		 Homo sapiens POLY [ADP-RIBOSE]
POLYMERASE 1		 PF00644
(PARP)
PF02877
(PARP_reg)		 11 GLN A 759
GLU A 763
HIS A 862
GLY A 863
TYR A 889
TYR A 896
ALA A 898
LYS A 903
SER A 904
TYR A 907
GLU A 988
 RPB A1103
4RV6_B_RPBB1103 4rv6 RPB

DB12332
(Rucaparib)		 Homo sapiens POLY [ADP-RIBOSE]
POLYMERASE 1		 no annotation 11 GLN B 759
GLU B 763
HIS B 862
GLY B 863
TYR B 889
TYR B 896
ALA B 898
LYS B 903
SER B 904
TYR B 907
GLU B 988
 RPB B1103