KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
2X7H_A_PFNA1372 2x7h PFN

DB00573
(Fenoprofen)		 Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2		 PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
no annotation		 11 TYR A 161
LEU A 164
LYS A 165
LEU A 170
LEU A 192
LYS A 195
THR B 277
PRO B 278
PRO B 283
HIS A 318
MET A 322
 PFN A1372
2X7H_A_PFNA1374 2x7h PFN

DB00573
(Fenoprofen)		 Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2		 PF00107
(ADH_zinc_N)
PF08240
(ADH_N)		 6 PRO A 144
SER A 145
LYS A 147
GLU A 149
TYR A 150
CYS A 323
 PFN A1374
2X7H_A_PFNA1375 2x7h PFN

DB00573
(Fenoprofen)		 Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2		 PF00107
(ADH_zinc_N)
PF08240
(ADH_N)		 5 SER A  77
TYR A  86
PHE A  98
VAL A 155
TYR A 275
 PFN A1375
2X7H_B_PFNB1372 2x7h PFN

DB00573
(Fenoprofen)		 Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2		 no annotation 5 SER B  77
TYR B  86
PHE B  98
VAL B 155
TYR B 275
 PFN B1372
2X7H_B_PFNB1374 2x7h PFN

DB00573
(Fenoprofen)		 Homo sapiens ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2		 no annotation 4 TYR B 161
LEU B 164
LEU B 192
HIS B 318
 PFN B1374