KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
4WVD_A_IVMA505 4wvd IVM

DB00602
(Ivermectin)		 Homo sapiens BILE ACID RECEPTOR PF00104
(Hormone_recep)		 11 GLU A 276
ASN A 283
LEU A 287
MET A 290
ASN A 293
HIS A 294
ARG A 331
SER A 332
ILE A 335
LEU A 348
MET A 365
 IVM A 505
5VDH_A_IVMA403 5vdh IVM

DB00602
(Ivermectin)		 Homo sapiens GLYCINE RECEPTOR
SUBUNIT ALPHA-3		 PF02932
(Neur_chan_memb)
PF02931
(Neur_chan_LBD)		 12 LEU B 224
GLN B 226
ILE B 229
PRO B 230
LEU B 233
THR A 264
SER A 267
SER A 268
VAL A 280
ALA A 288
LEU A 291
LEU A 292
 IVM A 403
5VDI_A_IVMA403 5vdi IVM

DB00602
(Ivermectin)		 Homo sapiens GLYCINE RECEPTOR
SUBUNIT ALPHA-3		 PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb)		 10 GLN B 226
ILE B 229
PRO B 230
LEU B 233
ILE B 236
THR A 264
SER A 267
VAL A 280
ALA A 288
LEU A 291
 IVM A 403