KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
3QX3_A_EVPA1 3qx3 EVP

DB00773
(Etoposide)		 Homo sapiens DNA TOPOISOMERASE
2-BETA		 PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C)		 5 GLY A 478
ASP A 479
ARG A 503
GLN A 778
MET A 782
 EVP A   1
3QX3_D_EVPD1 3qx3 EVP

DB00773
(Etoposide)		 ;
Homo sapiens		 DNA TOPOISOMERASE
2-BETA		 no annotation 5 GLY B 478
ASP B 479
ARG B 503
GLN B 778
MET B 782
 EVP D   1
4LB9_A_EVPA605 4lb9 EVP

DB00773
(Etoposide)		 Homo sapiens SERUM ALBUMIN PF00273
(Serum_albumin)		 10 ASP A 108
HIS A 146
TYR A 148
SER A 193
ARG A 197
CYS A 200
ALA A 201
GLN A 204
HIS A 247
GLY A 248
 EVP A 605
5GWK_D_EVPD102 5gwk EVP

DB00773
(Etoposide)		 Homo sapiens;
synthetic
construct		 DNA TOPOISOMERASE
2-ALPHA		 no annotation 4 GLY B 462
ASP B 463
ARG B 487
MET B 766
 EVP D 102
5GWK_F_EVPF102 5gwk EVP

DB00773
(Etoposide)		 Homo sapiens;
synthetic
construct		 DNA TOPOISOMERASE
2-ALPHA		 PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C)
no annotation		 5 GLY A 462
ASP A 463
ARG A 487
MET A 762
MET A 766
 EVP F 102