KNOWN TARGETS FROM HUMAN (PROTEIN-DRUG COMPLEXES IN THE PDB)

1) Click on the entry ID to view details of interfaces and pattern clusters
2) Note that ASSAM search use only 3-12 residue containing patterns
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM View
2AXN_A_EDTA737 2axn EDT

DB00974
(Edetic
Acid)		 Homo sapiens 6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105);
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)]		 PF00300
(6PF2K)
PF01591
(His_Phos_1)		 13 PRO A  43
LYS A  47
THR A  48
ASN A  69
GLY A  71
ARG A  74
ARG A  75
PHE A  87
ARG A  98
ALA A 125
THR A 126
ARG A 189
TYR A 193
 EDT A 737
3RNJ_A_EDTA1 3rnj EDT

DB00974
(Edetic
Acid)		 Homo sapiens BRAIN-SPECIFIC
ANGIOGENESIS
INHIBITOR
1-ASSOCIATED PROTEIN
2		 PF14604
(SH3_9)		 4 LYS A 380
ARG A 433
LEU A 435
ASP A 436
 EDT A   1
5JHD_E_EDTE301 5jhd EDT

DB00974
(Edetic
Acid)		 Homo sapiens BETA-2-MICROGLOBULIN
;
TCRBETA CHAIN		 None
PF07654
(V-set)
PF07686
(C1-set)		 8 TYR E  49
LYS E  59
SER E  67
THR E  79
ARG G  81
THR E  81
PRO G  90
ILE G  92
 EDT E 301
5JHD_J_EDTJ301 5jhd EDT

DB00974
(Edetic
Acid)		 Homo sapiens TCRBETA CHAIN None 5 TYR J  49
LYS J  59
GLU J  64
GLY J  65
SER J  67
 EDT J 301
5UIG_A_EDTA501 5uig EDT

DB00974
(Edetic
Acid)		 Escherichia
coli;
Homo sapiens		 ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A		 PF00001
(Cytochrom_B562)
PF07361
(7tm_1)		 6 ASN A  39
THR A  41
ASN A  42
ARG A 102
ILE A 292
GLU A 294
 EDT A 501
5UWC_G_EDTG407 5uwc EDT

DB00974
(Edetic
Acid)		 Homo sapiens INTERLEUKIN-3
RECEPTOR SUBUNIT
ALPHA		 PF09240
(IL6Ra-bind)		 5 TRP G 113
HIS G 115
SER G 121
LYS G 155
ARG G 166
 EDT G 407