010 DB06770 Benzyl alcohol Benzyl alcohol is an antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. 017 DB01264 Darunavir Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. 032 DB08881 Vemurafenib Vemurafenib is a kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. 06X DB00381 Amlodipine Amlodipine is a calcium channel blocker used to treat hypertension and angina. 08D DB01015 Sulfamethoxazole Sulfamethoxazole is an oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. 08H DB00404 Alprazolam Alprazolam is a triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. 08J DB00683 Midazolam Midazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. 08Y DB01200 Bromocriptine Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. 09L DB09074 Olaparib Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy. 0HK DB01409 Tiotropium Tiotropium is a long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). 0JM DB00578 Carbenicillin Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. 0LI DB08901 Ponatinib Ponatinib is a kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). 0RM DB01603 Meticillin One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection. 0RN DB09324 Sulbactam Sulbactam is an beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. 0RV DB00760 Meropenem Meropenem is a carbapenem antibiotic used to treat a wide variety of infections in the body. 0WM DB08916 Afatinib Afatinib is an antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. 0WO DB00713 Oxacillin Oxacillin is a penicillin antibiotic used to treat a number of susceptible bacterial infections. 115 DB01095 Fluvastatin Fluvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. 116 DB00439 Cerivastatin Cerivastatin is a statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. 117 DB01076 Atorvastatin Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. 142 DB00190 Carbidopa Carbidopa is a dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. 15M DB00905 Bimatoprost Bimatoprost is a prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. 15U DB00278 Argatroban Argatroban is a synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use. 16A DB01718 Cetrimonium Cetrimonium is a compound that can be used as a topical antiseptic. 1C6 DB00338 Omeprazole Omeprazole is a proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. 1C9 DB11963 Dacomitinib Dacomitinib is a medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. 1E8 DB09053 Ibrutinib Ibrutinib is an antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. 1FL DB00861 Diflunisal Diflunisal is an NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. 1KX DB01048 Abacavir Abacavir is an antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV. 1LD DB01099 Flucytosine Flucytosine is an antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. 1LT DB12015 Alpelisib Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid... 1N1 DB01254 Dasatinib Dasatinib is a tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. 1PQ DB01087 Primaquine Primaquine is an antimalarial indicated to prevent relapse of vivax malaria. 1PT DB00526 Oxaliplatin Oxaliplatin is a platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer. 1QL DB01331 Cefoxitin Cefoxitin is a semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection. 1RG DB00303 Ertapenem Ertapenem is a carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. 1UN DB00220 Nelfinavir Nelfinavir is a viral protease inhibitor used in the treatment of HIV infection. 1W8 DB06590 Ceftaroline fosamil Ceftaroline fosamil is an antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. 1WE DB01576 Dextroamphetamine Dextroamphetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. 1YN DB01167 Itraconazole Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. 20J DB01119 Diazoxide Diazoxide is a non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. 210 DB00282 Pamidronic acid Pamidronic acid is a bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions. 211 DB13747 Trolamine Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine... 212 DB00630 Alendronic acid Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. 21B DB00540 Nortriptyline Nortriptyline is a tricyclic antidepressant used in the treatment of depression. 225 DB01023 Felodipine Felodipine is a calcium channel blocker used to treat hypertension. 268 DB11304 Phenoxyethanol Phenoxyethanol is an antiseptic used as a hand disinfectant or preservative in medications. 27J DB11478 Zeranol Zeranol is a non-steroidal estrogen agonist. It is a mycotoxin, derived from fungi in the Fusarium family, and may be found as a contaminant in fungus-infected crops. It is 3-4x... 27R DB00963 Bromfenac Bromfenac is an NSAID used to treat postoperative pain and inflammation of the eye. 29E DB00476 Duloxetine Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. 29J DB06700 Desvenlafaxine Desvenlafaxine is an antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. 29Q DB00579 Mazindol Mazindol is a sympathomimetic used to treat obesity in combination with lifestyle modifications. 29S DB06401 Bazedoxifene Bazedoxifene is a selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens. 2AL DB11100 Allantoin Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. 2DI DB00900 Didanosine Didanosine is a reverse transcriptase inhibitor used to treat HIV. 2GM DB00320 Dihydroergotamine Dihydroergotamine is an ergot alkaloid used in the acute treatment of migraine headache and cluster headache. 2K2 DB06595 Midostaurin Midostaurin is an antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). 2KW DB12301 Doravirine Doravirine is a non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. 2MN DB00916 Metronidazole Metronidazole is a nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. 2PM DB01075 Diphenhydramine Diphenhydramine is a H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. 2PP DB00313 Valproic acid Valproic acid is an anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. 2Q2 DB13180 Gluconic acid Gluconic Acid is an electrolyte supplement used in total parenteral nutrition. 2R9 DB11586 Asunaprevir Asunaprevir is an NS3 protease inhibitor used to treat hepatitis C genotype 1b. 2RC DB12010 Fostamatinib Fostamatinib is a spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. 2SJ DB15534 Colchiceine Colchiceine is one of several metabolites of the anti-gout medication colchicine. 2TA DB12500 Fedratinib Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.[A183176,L8090] It is an anilinopyrimidine derivative. Fedratinib was... 2YQ DB11760 Talazoparib Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer. 308 DB00915 Amantadine Amantadine is a medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications. 30B DB06290 Simeprevir Simeprevir is a direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. 30Z DB00179 Masoprocol A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in... 356 DB08882 Linagliptin Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. 36M DB14177 Propylparaben Propylparaben is used in allergenic testing. 377 DB01043 Memantine Memantine is an NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's. 3BV DB08889 Carfilzomib Carfilzomib is a proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma. 3C0 DB11315 Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... 3CJ DB00550 Propylthiouracil Propylthiouracil is a thiourea antithyroid agent used to treat hyperthyroidism. 3EW DB11689 Selumetinib Selumetinib is a MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN). 3JD DB11793 Niraparib Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy. 3JW DB11817 Baricitinib Baricitinib is a Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. 3MI DB11644 Tafamidis Tafamidis is a medication used to treat transthyretin-mediated amyloidosis. 3NF DB11102 N-acetyltyrosine N-acetyltyrosine is an amino acid used in total parenteral nutrition. 3QB DB01627 Lincomycin Lincomycin is an antibiotic indicated only for the treatment of serious infections and is typically reserved for use in cases of penicillin allergy or where penicillin is inappropriate. 3T5 DB14669 Betamethasone phosphate Betamethasone phosphate is a fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. 3TC DB00709 Lamivudine Lamivudine is a reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. 3WF DB00977 Ethinylestradiol Ethinylestradiol is an estradiol used as a contraceptive. 40L DB09054 Idelalisib Idelalisib is an antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). 41X DB00234 Reboxetine Reboxetine is a drug used for the acute treatment of major depression and for maintenance therapy of depression. 478 DB00701 Amprenavir Amprenavir is a protease inhibitor used to treat HIV infection. 486 DB00834 Mifepristone Mifepristone is a cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. 4AP DB06637 Dalfampridine Dalfampridine is a potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS). 4AX DB00260 Cycloserine Cycloserine is a broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI). 4CH DB13154 Parachlorophenol Parachlorophenol is an antibacterial agent used to prevent infections in root canals. 4D6 DB12107 Vaborbactam Vaborbactam is a beta lactamase inhibitor used to treat complicated urinary tract infections. 4DW DB00642 Pemetrexed Pemetrexed is a folate analog used to treat mesothelioma and non-small cell lung cancer. 4DY DB06774 Capsaicin Capsaicin is a topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain. 4KO DB00274 Cefmetazole Cefmetazole is a cephalosporin antibiotic used to treat a variety of bacterial infections. 4KS DB09516 Mequinol Mequinol is a topical agent used in combination with tretinoin to treat solar lentigines. 4MK DB09063 Ceritinib Ceritinib is an antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. 4PZ DB01213 Fomepizole Fomepizole is an inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. 4TX DB01241 Gemfibrozil Gemfibrozil is a lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. 5AE DB00928 Azacitidine Azacitidine is a pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome. 5CH DB01628 Etoricoxib Etoricoxib is a selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. 5FW DB01064 Isoprenaline Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. 5OG DB05015 Belinostat Belinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). 5P8 DB12130 Lorlatinib Lorlatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. 5RL DB00714 Apomorphine Apomorphine is a morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. 5SF DB12147 Erdafitinib Erdafitinib is a fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma. 5WQ DB01045 Rifampicin Rifampicin is an antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. 62W DB00742 Mannitol Mannitol is a sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. 64Z DB14183 Geraniol Geraniol is a monoterpene that is found within many essential oils of fruits, vegetables, and herbs including rose oil, citronella, lemongrass, lavender, and other aromatic plants. It is emitted from... 657 DB00740 Riluzole Riluzole is a glutamate antagonist used to treat amyotrophic lateral sclerosis. 65B DB06414 Etravirine Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. 68H DB13139 Levosalbutamol Levosalbutamol is a beta-2 adrenergic receptor agonist used to treat COPD and asthma. 68P DB01175 Escitalopram Escitalopram is a selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). 69Q DB13874 Enasidenib Enasidenib is an isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. 6E2 DB12483 Copanlisib Copanlisib is a medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments. 6EL DB01041 Thalidomide Thalidomide is a medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum. 6GY DB12267 Brigatinib Brigatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. 6K9 DB08871 Eribulin Eribulin is a microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma. 6LH DB06795 Mafenide Mafenide is an antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. 6T0 DB00724 Imiquimod Imiquimod is a toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata. 6U9 DB00393 Nimodipine Nimodipine is a calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. 6UB DB09237 Levamlodipine Levamlodipine is a calcium channel blocker used to treat hypertension. 6UV DB00563 Methotrexate Methotrexate is an antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. 6V8 DB09570 Ixazomib Ixazomib is a monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. 6ZP DB08883 Perampanel Perampanel is a non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. 6ZV DB12001 Abemaciclib Abemaciclib is a medication used to treat HR+ HER2- advanced or metastatic breast cancer. 6ZZ DB11730 Ribociclib Ribociclib is a kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer. 715 DB01261 Sitagliptin Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. 71R DB11512 Dihydrostreptomycin Dihydrostreptomycin is an antibiotic. 7A9 DB00377 Palonosetron Palonosetron is a serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. 7HP DB00437 Allopurinol Allopurinol is a xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. 7KP DB11263 Polydatin Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin... 7V7 DB00813 Fentanyl Fentanyl is an opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. 803 DB00227 Lovastatin Lovastatin is an HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. 84D DB13270 Dibekacin Dibekacin is an aminoglycoside antibiotic marketed in Japan . 8CV DB00914 Phenformin A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often... 8MO DB00553 Methoxsalen Methoxsalen is a furocoumarin used to treat psoriasis and vitiligo. 8N6 DB01132 Pioglitazone Pioglitazone is a thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. 8NU DB00734 Risperidone Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. 8PR DB00715 Paroxetine Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. 8QP DB00749 Etodolac Etodolac is an NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. 8W5 DB01222 Budesonide Budesonide is a corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. 8YF DB01598 Imipenem Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. 911 DB01077 Etidronic acid Etidronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis. 95E DB00330 Ethambutol Ethambutol is an antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). 95Z DB01296 Glucosamine Glucosamine is a common ingredient in nutritional supplements used for the relief of joint pain. 970 DB11457 Rotenone Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also... 9CR DB00523 Alitretinoin Alitretinoin is a vitamin A derivative used to treat Kaposi's sarcoma and used off label to treat chronic hand eczema and psoriasis. 9DC DB06782 Dimercaprol Dimercaprol is a chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium. 9EG DB11155 Triclocarban Triclocarban is an antibacterial agent used in liquid soaps and body washes. 9EP DB00456 Cefalotin Cefalotin is a broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract. 9F2 DB01212 Ceftriaxone Ceftriaxone is a broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract. 9HB DB08908 Dimethyl fumarate Dimethyl fumarate is a medication used to treat patients with the relapsing-remitting form of multiple sclerosis. 9KL DB09214 Dexketoprofen Dexketoprofen is an NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain. 9PL DB01085 Pilocarpine Pilocarpine is a muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. 9RA DB00307 Bexarotene Bexarotene is a retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. 9SC DB01238 Aripiprazole Aripiprazole is an atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. 9TP DB00444 Teniposide Teniposide is a cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. 9UQ DB00357 Aminoglutethimide Aminoglutethimide is an adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome. 9V2 DB00593 Ethosuximide Ethosuximide is an anticonvulsant used to treat petit mal seizures. 9WT DB01413 Cefepime Cefepime is a fourth-generation cephalosporin antibiotic used in the treatment of various bacterial infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections. 9Y6 DB14184 Cinnamaldehyde Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus... A0B DB13911 Phloxine b Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to... A26 DB08880 Teriflunomide Teriflunomide is a pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. A4Z DB13346 Bufexamac Bufexamac is an NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. A9L DB05676 Apremilast Apremilast is a non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis. AB1 DB01601 Lopinavir Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. ABU DB02530 Gamma-aminobutyric acid The most common inhibitory neurotransmitter in the central nervous system. AC2 DB00787 Acyclovir Acyclovir is a guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster. ACA DB00513 Aminocaproic acid Aminocaproic acid is an antifibrinolytic agent used to induce clotting postoperatively. ACH DB03128 Acetylcholine Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. AEG DB09352 Hydroxyamphetamine Hydroxyamphetamine is an indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. AER DB05812 Abiraterone Abiraterone is an antiandrogen used in the treatment of prostate cancer. AGG DB00775 Tirofiban Tirofiban is a platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome. AIC DB00415 Ampicillin Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. AIN DB00945 Acetylsalicylic acid Aspirin is a salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. AJM DB01426 Ajmaline Ajmaline is an antiarrhythmic used to manage a variety of forms of tachycardias. AKN DB00479 Amikacin Amikacin is an aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria. ALE DB00668 Epinephrine Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. AM2 DB04626 Apramycin Apramycin is an aminoglycoside antibiotic for veterinary use that is used to treat infections in animals. AMH DB00302 Tranexamic acid Tranexamic acid is an antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders. AMJ DB06218 Lacosamide Lacosamide is an antiepileptic drug used to treat partial onset seizures in adults. AMR DB00594 Amiloride Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure. ANW DB01025 Amlexanox Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent... AOQ DB01117 Atovaquone Atovaquone is an antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. AQ4 DB00530 Erlotinib Erlotinib is an EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers. AR3 DB00987 Cytarabine Cytarabine is a pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. ASR DB03006 Arsanilic acid An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] ASW DB00276 Amsacrine Amsacrine is a cytotoxic agent used to induce remission in acute adult leukemia that is not adequately responsive to other agents. AWY DB06594 Agomelatine Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine... AXI DB06626 Axitinib Axitinib is an oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. AY6 DB06155 Rimonabant Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite.... AZ1 DB00548 Azelaic acid Azelaic acid is a saturated dicarboxylic acid used to treat mild to moderate acne vulgaris. AZM DB00819 Acetazolamide Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. AZR DB00355 Aztreonam Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. AZZ DB00495 Zidovudine Zidovudine is a dideoxynucleoside used in the treatment of HIV infection. B1T DB04813 Bithionol Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the... B40 DB01577 Metamfetamine Metamfetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. B49 DB01268 Sunitinib Sunitinib is a receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). B4O DB01188 Ciclopirox Ciclopirox is a broad-spectrum topical antifungal agent used to treat mild to moderate onychomycosis of fingernails and toenails in immunocompetent patients. BA0 DB15035 Zanubrutinib Zanubrutinib is a kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy. BAX DB00398 Sorafenib Sorafenib is a kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. BBI DB01118 Amiodarone Amiodarone is a class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. BCZ DB06614 Peramivir Peramivir is an intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days. BEP DB01244 Bepridil A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts... BER DB04115 Berberine An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... BFQ DB00710 Ibandronate Ibandronate is a bisphosphonate used to treat osteoporosis in postmenopausal women. BHA DB00233 Aminosalicylic acid Aminosalicylic acid is an aminosalicylate drug used to induce remission in ulcerative colitis. BJX DB00912 Repaglinide Repaglinide is a antihyperglycemic used to improve glycemic control in diabetes. BLM DB00290 Bleomycin Bleomycin is a chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others. BLQ DB01014 Balsalazide Balsalazide is an aminosalicylate used to treat ulcerative colitis. BO2 DB00188 Bortezomib Bortezomib is a proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. BO3 DB11326 Boric acid Boric acid, also known as hydrogen borate, is a weak monobasic Lewis acid of boron with the chemical formula H3BO3. Boric acid is typically utilized in industrial processing and manufacturing,... BQ1 DB08903 Bedaquiline Bedaquiline is a diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). BRL DB00412 Rosiglitazone Rosiglitazone is a thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. BS4 DB09355 Sulfabenzamide Sulfabenzamide is a sulfonamide antibacterial used as an ingredient in various topical and vaginal preparations to treat certain infections, but has been discontinued by the FDA. BUW DB00392 Profenamine Profenamine is an antidyskinetic phenothiazine used to treat the symptoms of Parkinson's disease. BVD DB03312 Brivudine Brivudine is a drug used to treat herpes zoster. BZ1 DB01194 Brinzolamide Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. BZM DB00676 Benzyl benzoate Benzyl benzoate is a topical treatment for scabies and lice. C04 DB00671 Cefixime Cefixime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. C3D DB06202 Lasofoxifene Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention... C41 DB09026 Aliskiren Aliskiren is a direct renin inhibitor used to manage hypertension. C5U DB01115 Nifedipine Nifedipine is a dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. C6F DB12141 Gilteritinib Gilteritinib is an AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia. C7H DB00434 Cyproheptadine Cyproheptadine is a combined serotonin and histamine antagonist used in the treatment of allergic symptoms, for appetite stimulation, and off-label in the treatment of serotonin syndrome. C9F DB00343 Diltiazem Diltiazem is a calcium channel blocker used to treat hypertension and to manage chronic stable angina. CA4 DB04839 Cyproterone acetate Cyproterone acetate is a steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer CBE DB04657 Carboxin A systemic agricultural fungicide and seed treatment agent. CBL DB00291 Chlorambucil Chlorambucil is a chemotherapy agent used in the management of chronic lymphocytic leukemia and malignant lymphomas. CC9 DB11672 Curcumin Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial,... CCE DB00411 Carbamoylcholine Carbachol is a direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. CCS DB04339 Carbocisteine Carbocisteine is a expectorant mucolytic used in the relief of respiratory of COPD and other conditions associated with increased mucus viscosity. CDC DB12153 Citicoline Citicoline is an endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. CDX DB00380 Dexrazoxane Dexrazoxane is a cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. CE3 DB00493 Cefotaxime Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. CE9 DB06811 Polidocanol Polidocanol is a sclerosing agent used for the treatment of uncomplicated spider veins and uncomplicated reticular veins, all less than 3 mm in diameter, in the lower extremity. CEL DB00482 Celecoxib Celecoxib is an NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. CFB DB00631 Clofarabine Clofarabine is a purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old. CFF DB00201 Caffeine Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. CGE DB00758 Clopidogrel Clopidogrel is an antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. CHC DB05990 Obeticholic acid Obeticholic acid is a bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. CHD DB02659 Cholic acid Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. CHZ DB04816 Dantron Dantron is a drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. CIA DB00820 Tadalafil Tadalafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. CIL DB01597 Cilastatin Cilastatin is a renal dehydropeptidase inhibitor used to prevent degradation of imipenem. Both medications are used together to treat a variety of infections. CL6 DB00257 Clotrimazole Clotrimazole is a topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. CL8 DB07565 Chloramphenicol succinate Chloramphenicol succinate is a broad-spectrum antibiotic agent used for the treatment of acute and severe infections caused by susceptible bacterial strains. CL9 DB00242 Cladribine Cladribine is a purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs. CLM DB00446 Chloramphenicol Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. CLQ DB00608 Chloroquine Chloroquine is an antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. CLT DB06819 Phenylbutyric acid Phenylbutyric acid is an agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. CLU DB00575 Clonidine Clonidine is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. CLW DB00356 Chlorzoxazone Chlorzoxazone is a drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. CLY DB01190 Clindamycin Clindamycin is a lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. CMU DB09343 Tipiracil Tipiracil is a thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies. COM DB09110 Coenzyme m Coenzyme M is a uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract. COX DB00580 Valdecoxib Valdecoxib is a COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. CP0 DB00762 Irinotecan Irinotecan is an antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. CP6 DB00205 Pyrimethamine Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. CPF DB00537 Ciprofloxacin Ciprofloxacin is a second generation fluoroquinolone used to treat various susceptible bacterial infections. CPT DB00515 Cisplatin Cisplatin is a platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. CQA DB00613 Amodiaquine Amodiaquine is an antimalarial drug. CQL DB04815 Clioquinol Clioquinol is an antifungal cream used to treat a variety of fungal infections. CTC DB09093 Chlortetracycline Chlortetracycline is the first tetracycline antibiotic most commonly used for veterinary purposes. CTX DB00675 Tamoxifen Tamoxifen is a selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. CTY DB01211 Clarithromycin Clarithromycin is a macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. CU9 DB01336 Metocurine Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. CVD DB01136 Carvedilol Carvedilol is a non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. CVI DB00406 Gentian violet cation Gentian Violet is an antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. CWB DB00889 Granisetron Granisetron is a 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. CXQ DB00245 Benzatropine Benzatropine is an anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia. CXX DB01242 Clomipramine Clomipramine is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. CYZ DB00606 Cyclothiazide As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides... CZE DB00341 Cetirizine Cetirizine is a selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. CZX DB00633 Dexmedetomidine Dexmedetomidine is an alpha-2 agonist used for sedation during various procedures. D16 DB00293 Raltitrexed Raltitrexed is a folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer. D8Z DB06697 Artemether Artemether is an antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. D95 DB09274 Artesunate Artesunate is artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. DAH DB01235 Levodopa Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. DB8 DB06616 Bosutinib Bosutinib is an antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. DCF DB00552 Pentostatin Pentostatin is an adenosine deaminase inhibitor used to treat hairy cell leukemia. DE3 DB11282 Diethyltoluamide Diethyltoluamide is an insect repellant, also known as DEET. DEQ DB04209 Dequalinium Dequalinium is a quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis. DES DB00255 Diethylstilbestrol A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report... DEX DB01234 Dexamethasone Dexamethasone is a glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. DGJ DB05018 Migalastat Migalastat is an alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant. DGX DB00390 Digoxin Digoxin is a cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. DHL DB00847 Cysteamine Cysteamine is a cystine depleting agent used to treat the effects of cystinosis. DIF DB00586 Diclofenac Diclofenac is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. DLU DB08930 Dolutegravir Dolutegravir is an antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. DM1 DB00694 Daunorubicin Daunorubicin is an anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. DM2 DB00997 Doxorubicin Doxorubicin is a medication used to treat various cancers and Kaposi's Sarcoma. DM5 DB01177 Idarubicin Idarubicin is an anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults. DME DB01245 Decamethonium Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic... DOL DB01764 Dalfopristin Dalfopristin is an antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes. DP0 DB00280 Disopyramide Disopyramide is a class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. DR7 DB01072 Atazanavir Atazanavir is an antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. DSF DB01189 Desflurane Desflurane is a general inhalation anesthetic for inpatient and outpatient surgery in adults. DSM DB01151 Desipramine Desipramine is a tricyclic antidepressant used in the treatment of depression. DX2 DB00384 Triamterene Triamterene is a potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. DX4 DB00352 Tioguanine Tioguanine is a purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias. DXF DB01112 Cefuroxime Cefuroxime is a cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo. DXT DB00254 Doxycycline Doxycycline is a tetracycline antibiotic used to treat a wide variety of bacterial infections. DZP DB00829 Diazepam Diazepam is a long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. E53 DB01590 Everolimus Everolimus is a mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. E5E DB00368 Norepinephrine Norepinephrine is a sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. E6L DB06237 Avanafil Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction. EAA DB00903 Etacrynic acid Etacrynic acid is a diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. EAL DB09477 Enalaprilat Enalaprilat is an antihypertensive agent used for the management of hypertension when oral therapy is not practical. EDN DB14189 Ethylenediamine Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological... EDP DB00599 Thiopental Thiopental is a barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. EDR DB01010 Edrophonium Edrophonium is a cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. EDS DB12615 Plazomicin Plazomicin is an aminoglycoside antibiotic used to treat complicated urinary tract infections. EFZ DB00625 Efavirenz Efavirenz is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. ELV DB09101 Elvitegravir Elvitegravir is an antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. EMH DB11363 Alectinib Alectinib is a kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. ERG DB04038 Ergosterol A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS... ERM DB00696 Ergotamine Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. ERY DB00199 Erythromycin Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections. ESL DB04573 Estriol Estriol is a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching. EST DB00783 Estradiol Estradiol is an estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. ETS DB00869 Dorzolamide Dorzolamide is a carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. ETV DB00879 Emtricitabine Emtricitabine is a nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV. EUG DB14188 Isoeugenol Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic... EUI DB05239 Cobimetinib Cobimetinib is an antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma. EV1 DB01113 Papaverine Papaverine is an alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". EVP DB00773 Etoposide Etoposide is a podophyllotoxin derivative used to treat testicular and small cell lung tumors. EXM DB00990 Exemestane Exemestane is an aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. F0F DB04896 Milnacipran Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. F1U DB00193 Tramadol Tramadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. F5A DB13873 Fenofibric acid Fenofibric acid is a fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. F5O DB11979 Elagolix Elagolix is a gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis. F9E DB01610 Valganciclovir Valganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). F9R DB01396 Digitoxin Digitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. FBI DB01098 Rosuvastatin Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. FBX DB04953 Ezogabine Ezogabine is an antiepileptic agent used as an adjuvant treatment of partial-onset seizures. FCN DB00828 Fosfomycin Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections. FFO DB11596 Levoleucovorin Levoleucovorin is a folate analog used after high dose methotrexate for osteosarcoma, to reduce the toxic effects of folate analogs, and with 5-fluorouracil in palliative treatment of advanced metastatic colorectal cancer. FGT DB04824 Phenolphthalein Phenolphthalein is a drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. FI8 DB08874 Fidaxomicin Fidaxomicin is a macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. FIT DB01216 Finasteride Finasteride is an antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. FJQ DB01007 Tioconazole Tioconazole is an imidazole antifungal used to treat vulvovaginal candidiasis. FK5 DB00864 Tacrolimus Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. FL7 DB00690 Flurazepam Flurazepam is a long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. FLF DB02266 Flufenamic acid Flufenamic acid is an analgesic drug used to relieve pain associated with rheumatoid diseases. FLP DB00712 Flurbiprofen Flurbiprofen is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. FLU DB00693 Fluorescein Fluorescein is a dye used in angiography or angioscopy of the iris and retina. FMM DB01259 Lapatinib Lapatinib is an antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments. FO9 DB00927 Famotidine Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. FRD DB00182 Amphetamine Amphetamine is a CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). FUA DB02703 Fusidic acid Fusidic acid is a topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. FUN DB00695 Furosemide Furosemide is a loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. FUR DB00614 Furazolidone Furazolidone is a drug for the treatment of infectious diarrhea. FVK DB13781 Xamoterol Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... FVS DB00947 Fulvestrant Fulvestrant is an estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. FVT DB00855 Aminolevulinic acid Aminolevulinic acid is a porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma. FVX DB00176 Fluvoxamine Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. FY5 DB04574 Estrone sulfate Estrone sulfate is an estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. FYG DB09060 Avibactam Avibactam is a non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia. FYP DB01205 Flumazenil Flumazenil is a benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic procedures. G3C DB00800 Fenoldopam Fenoldopam is a dopamine D1 receptor agonist used for the short term management of hypertension. G65 DB11526 Masitinib Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in dogs. It has been available in Europe since 2009, under the brand name Masivet. In the... G6L DB00413 Pramipexole Pramipexole is a non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). GA2 DB01004 Ganciclovir Ganciclovir is a DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye. GAW DB09048 Netupitant Netupitant is an antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy. GBM DB01016 Glyburide Glyburide is a sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. GBN DB00996 Gabapentin Gabapentin is an anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures. GBQ DB00673 Aprepitant Aprepitant is a substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. GCZ DB01120 Gliclazide Gliclazide is a sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. GD4 DB00197 Troglitazone Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone. GEO DB00441 Gemcitabine Gemcitabine is a nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer. GG2 DB06605 Apixaban Apixaban is an anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. GM4 DB00652 Pentazocine Pentazocine is an analgesic used to treat moderate to severe pain. GMJ DB00502 Haloperidol Haloperidol is an antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. GMR DB00222 Glimepiride Glimepiride is a sulfonylurea drug used to treat type 2 diabetes mellitus. GNT DB00674 Galantamine Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. GW6 DB08906 Fluticasone furoate Fluticasone furoate is an inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. GZX DB04845 Ixabepilone Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. H3P DB00756 Hexachlorophene Hexachlorophene is a chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser. H8D DB00353 Methylergometrine Methylergometrine is an ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. H8G DB00589 Lisuride An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at... H8J DB00247 Methysergide Methysergide is an ergot alkaloid used for the prophylaxis of migraine and cluster headaches. H98 DB01274 Arformoterol Arformoterol is a beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. HAE DB00551 Acetohydroxamic acid Acetohydroxamic acid is a synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. HCY DB00741 Hydrocortisone Hydrocortisone is a glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. HCZ DB00999 Hydrochlorothiazide Hydrochlorothiazide is a thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. HDZ DB09152 Nitrogen Nitrogen is a cryogenic agent used to treat various benign and malignant skin lesions. HFG DB04866 Halofuginone Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis... HFT DB00499 Flutamide Flutamide is an antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. HFZ DB00774 Hydroflumethiazide Hydroflumethiazide is a thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. HLT DB01159 Halothane Halothane is a general inhalation anesthetic used for the induction and maintenance of general anesthesia. HLZ DB01275 Hydralazine Hydralazine is an antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia . HQE DB09526 Hydroquinone Hydroquinone is a topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. HQI DB11145 Oxyquinoline Oxyquinoline is a medication used in combination with other medications to restore vaginal pH. HSM DB05381 Histamine Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. HSY DB09419 Xylose Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood. D-Xylose is a sugar widely... HUP DB04864 Huperzine a Huperzine A, is a naturally occurring sesquiterpene alkaloid found in the extracts of the firmoss Huperzia serrata. The botanical has been used in China for centuries for the treatment of... HXA DB03756 Doconexent Doconexent is an omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. HY0 DB11520 Hygromycin b Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. HYO DB00424 Hyoscyamine Hyoscyamine is an anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. I7A DB01144 Diclofenamide Diclofenamide is a carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. IBP DB09213 Dexibuprofen Dexibuprofen is a pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. ICD DB08942 Isoxicam Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. ICF DB00753 Isoflurane Isoflurane is an inhaled general anesthetic used in surgery. ID2 DB00249 Idoxuridine Idoxuridine is a pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. ID8 DB00784 Mefenamic acid Mefenamic acid is an NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. IDB DB04711 Iodipamide Iodipamide is a contrast agent used in cholangiography and cholecystography. IL2 DB01088 Iloprost Iloprost is a synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH). IM4 DB11421 Imidacloprid Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and... IMN DB00328 Indomethacin Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. INS DB13178 Inositol Inositol is an ingredient found in a variety of nutritional products. IRE DB00317 Gefitinib Gefitinib is a tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. ISZ DB00951 Isoniazid Isoniazid is an antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis. IU5 DB01586 Ursodeoxycholic acid Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. IVM DB00602 Ivermectin Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. IXX DB00458 Imipramine Imipramine is a tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. IZP DB01050 Ibuprofen Ibuprofen is an NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. J01 DB00766 Clavulanic acid Clavulanic acid is a beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics. J3Z DB00655 Estrone Estrone is an estrogen used to treat perimenopausal and postmenopausal symptoms. JEV DB00980 Ramelteon Ramelteon is a melatonin receptor agonist used to treat insomnia. JMS DB00939 Meclofenamic acid Meclofenamic acid is an NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. JN3 DB06777 Chenodeoxycholic acid Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis. JZ3 DB11359 Guaiacol Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.... K4D DB01195 Flecainide Flecainide is a class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). K5Y DB00938 Salmeterol Salmeterol is a long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. K86 DB00559 Bosentan Bosentan is a dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. KAN DB01172 Kanamycin Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. KKK DB01026 Ketoconazole Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. KLQ DB11799 Bictegravir Bictegravir is an integrase inhibitor used to treat HIV infections. KTR DB00465 Ketorolac Ketorolac is an NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. KXN DB14086 Cianidanol An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms. L89 DB11640 Amifampridine Amifampridine is a voltage gated potassium channel blocker used to treat Lambert-Eaton myasthenic syndrome. L8P DB00369 Cidofovir Cidofovir is an antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS. L9P DB12026 Voxilaprevir Voxilaprevir is a nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. LBH DB06603 Panobinostat Panobinostat is a non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. LBM DB11581 Venetoclax Venetoclax is a BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. LCR DB06282 Levocetirizine Levocetirizine is an H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. LDP DB00988 Dopamine Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. LEI DB00859 Penicillamine Penicillamine is a chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis. LEV DB09078 Lenvatinib Lenvatinib is a receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. LF7 DB04876 Vildagliptin Vildagliptin is a once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. LLT DB01265 Telbivudine Telbivudine is a thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST). LOC DB01394 Colchicine Colchicine is an alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). LPR DB00722 Lisinopril Lisinopril is an ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. LQQ DB09073 Palbociclib Palbociclib is an endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer. LQZ DB00281 Lidocaine Lidocaine is a local anesthetic used in a wide variety of superficial and invasive procedures. LSD DB11423 Lasalocid Lasalocid is an agent that presents antibacterial and coccidiostat activities. It is produced by strains of Streptomyces lasaliensis. LSN DB00678 Losartan Losartan is an angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. LUR DB01283 Lumiracoxib Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in... LZU DB00679 Thioridazine Thioridazine is a phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder. M0E DB11377 Bambermycins Bambermycins are antibiotic complexes which are retrieved from the organism, Streptomyces bambergiensis. They are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics... M4Y DB13063 Parthenolide Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. MC9 DB02300 Calcipotriol Calcipotriol is a topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis. MF8 DB00331 Metformin Metformin is a biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS). MI1 DB08895 Tofacitinib Tofacitinib is a Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine. MIG DB00491 Miglitol Miglitol is an oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates. MIL DB00235 Milrinone Milrinone is a PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. MIX DB01204 Mitoxantrone Mitoxantrone is a chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. MIY DB01017 Minocycline Minocycline is a tetracycline analog used to treat a wide variety of infections in the body. MK1 DB00224 Indinavir Indinavir is a protease inhibitor used to treat HIV infection. MMZ DB00763 Methimazole Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. MOA DB01024 Mycophenolic acid Mycophenolic acid is an immunosuppressant used to prevent organ transplant rejections. MOF DB14512 Mometasone furoate Mometasone furoate is a corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. MOI DB00295 Morphine Morphine is an opioid agonist used for the relief of moderate to severe acute and chronic pain. MPB DB14212 Methylparaben Methylparaben is used in allergenic testing. MRC DB00410 Mupirocin Mupirocin is an antibacterial ointment used to treat impetigo and secondary skin infections caused by Staphylococcus aureus and Streptococcus pyogenes. MRV DB04835 Maraviroc Maraviroc is a CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. MTK DB00471 Montelukast Montelukast is a leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. MV2 DB09357 Dexpanthenol Dexpanthenol is an alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). MXD DB00350 Minoxidil Minoxidil is an antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage. MXM DB00814 Meloxicam Meloxicam is an NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. MYT DB01011 Metyrapone Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. MZM DB00703 Methazolamide Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. N6W DB00564 Carbamazepine Carbamazepine is an anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. NBO DB00461 Nabumetone Nabumetone is an NSAID used to treat osteoarthritis and rheumatoid arthritis. NBV DB00419 Miglustat Miglustat is a glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. NCT DB00184 Nicotine Nicotine is a stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. NDR DB00717 Norethisterone Norethisterone is a synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis. NFF DB00607 Nafcillin Nafcillin is a penicillin derivative antibiotic used to treat susceptible staphylococcal infections. NFZ DB00336 Nitrofural Nitrofural is a topical antibacterial for the prevention and treatment of bacterial infections of the skin. NH3 DB11118 Ammonia Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium... NHY DB01005 Hydroxyurea Hydroxyurea is an antimetabolite used to treat sickle cell anemia crisis. NIL DB04868 Nilotinib Nilotinib is a kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. NIM DB04743 Nimesulide Nimesulide is a cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. NMM DB11815 Tilarginine Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow. NMY DB00452 Framycetin Framycetin is an aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. NOG DB00367 Levonorgestrel Levonorgestrel is a progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives. NOV DB01051 Novobiocin Novobiocin is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds,... NPS DB00788 Naproxen Naproxen is an NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. NRK DB11951 Lemborexant Lemborexant is a dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. NTI DB00507 Nitazoxanide Nitazoxanide is a thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses. NVP DB00238 Nevirapine Nevirapine is a non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. O31 DB13879 Glecaprevir Glecaprevir is a Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. O6P DB06211 Doripenem Doripenem is an antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. OAQ DB01096 Oxamniquine An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp. Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms... OBN DB01092 Ouabain A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell... OHB DB08797 Salicylamide Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... OIN DB00572 Atropine Atropine is a muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. OLM DB00275 Olmesartan Olmesartan is an angiotensin receptor blocker (ARB) used in the treatment of hypertension. OPB DB03585 Oxyphenbutazone Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. OTC DB00595 Oxytetracycline Oxytetracycline is a tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. OXC DB03209 Oteracil Oteracil is a chemotherapy agent used in combination with tegafur, cisplatin and gimeracil to treat advanced gastric cancer. P06 DB08912 Dabrafenib Dabrafenib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. P0T DB09061 Cannabidiol Cannabidiol is an active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. P1Z DB00812 Phenylbutazone Phenylbutazone is an NSAID used to treat backache and ankylosing spondylitis. P2E DB00917 Dinoprostone Dinoprostone is a prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. P2Z DB00420 Promazine Promazine is a phenothiazine used to manage schizophrenia. P31 DB12978 Pexidartinib Pexidartinib is an antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. P77 DB00433 Prochlorperazine Prochlorperazine is a phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. PAB DB02362 Aminobenzoic acid Aminobenzoic acid is a drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. PAC DB09269 Phenylacetic acid Phenylacetic acid is an agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. PAR DB01421 Paromomycin Paromomycin is an aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. PD9 DB00494 Entacapone Entacapone is a selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. PDN DB00635 Prednisone Prednisone is a corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. PE2 DB00299 Penciclovir Penciclovir is a topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis. PEM DB01393 Bezafibrate Bezafibrate is a lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. PFN DB00573 Fenoprofen Fenoprofen is an anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. PL3 DB09494 Cetyl alcohol Cetyl alcohol, also known as 1-hexadecanol or n-hexadecyl alcohol, is a 16-C fatty alcohol with the chemical formula CH3(CH2)15OH. It can be produced from the reduction of palmitic acid. Cetyl... PLO DB02789 Pregnenolone A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. PM6 DB01033 Mercaptopurine Mercaptopurine is an antineoplastic agent used to treat acute lymphocytic leukemia. PNN DB01053 Benzylpenicillin Benzylpenicillin is a penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. PNT DB00738 Pentamidine Pentamidine is an antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. PNV DB00417 Phenoxymethylpenicillin Phenoxymethylpenicillin is a penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues. PNX DB00806 Pentoxifylline Pentoxifylline is a methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs. POD DB01179 Podofilox Podofilox is a topical agent used for the treatment of external genital warts and perianal warts. PPF DB00529 Foscarnet Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections. PQN DB01022 Phylloquinone Vitamin K1 is a fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. PRL DB01123 Proflavine Proflavine is a topical antiseptic agent used in wound dressings to prevent infections. PS9 DB09353 Octasulfur Sulfur is an ingredient of various cosmetic preparations for its keratolytic, antifungal, and antibacterial properties. PX9 DB09345 Pramocaine Pramocaine is a local anesthetic and antipruritic agent found in various topical preparations. PXB DB08439 Parecoxib Parecoxib is a selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. PZA DB00339 Pyrazinamide Pyrazinamide is an antituberculosis agent used as a component of tuberculosis (TB) treatment. PZE DB00592 Piperazine Piperazine is a medication used to treat roundworm and pinworm. PZI DB09210 Piracetam Piracetam is a nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer. QA1 DB01406 Danazol Danazol is a synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts. QDN DB00908 Quinidine Quinidine is a medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. QEL DB08954 Ifenprodil N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer... QI9 DB00468 Quinine Quinine is an alkaloid used to treat uncomplicated Plasmodium falciparum malaria. QKM DB11633 Isavuconazole Isavuconazole is an triazole antifungal with broad spectrum of activity and good safety profile . It is approved by the FDA and EMA for the treatment of invasive aspergillosis and... QMR DB01273 Varenicline Varenicline is a partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. QO7 DB11967 Binimetinib Binimetinib is a medication used to treat metastatic melanoma with specific mutations. QOM DB08911 Trametinib Trametinib is a kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. QPT DB00958 Carboplatin Carboplatin is a alkylating agent used to treat advanced ovarian cancer. R1Q DB00541 Vincristine Vincristine is a vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. RAB DB00194 Vidarabine Vidarabine is an antiviral agent used to treat various viral infections. RAL DB00481 Raloxifene Raloxifene is a selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. RAP DB00877 Sirolimus Sirolimus is an immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. RAS DB01367 Rasagiline Rasagiline is an irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa. RAV DB00312 Pentobarbital Pentobarbital is a barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. RB6 DB04918 Ceftobiprole Ceftobiprole is a cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. RBT DB00615 Rifabutin Rifabutin is an antibiotic used to treat mycobacterium avium complex disease in patients with HIV. RBV DB00811 Ribavirin Ribavirin is a guanosine nucleoside used to treat some forms of Hepatitis C. RCO DB11085 Resorcinol Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders... RCX DB00533 Rofecoxib Rofecoxib is a COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. RFV DB11753 Rifamycin Rifamycin is an antibacterial used to treat traveler's diarrhea. RG4 DB08877 Ruxolitinib Ruxolitinib is a kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment. RIM DB00478 Rimantadine Rimantadine is an RNA synthesis inhibitor used to prevent influenza A infection. RIO DB03615 Ribostamycin Ribostamycin is a broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. RIS DB00884 Risedronic acid Risedronic acid is a bisphosphonate used to treat osteoporosis and Paget's disease. RIT DB00503 Ritonavir Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. RIV DB06228 Rivaroxaban Rivaroxaban is a factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. RLT DB06817 Raltegravir Raltegravir is an antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals. ROC DB01232 Saquinavir Saquinavir is an HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. ROF DB01656 Roflumilast Roflumilast is a selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis. RPB DB12332 Rucaparib Rucaparib is an anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. RPT DB01201 Rifapentine Rifapentine is an antibiotic agent used in the treatment of pulmonary tuberculosis. RXM DB01220 Rifaximin Rifaximin is a rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. S7W DB09256 Tegafur Tegafur is an antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers. S7Y DB00969 Alosetron Alosetron is a 5-HT3 antagonist used to treat diarrhea-predominant IBS. S87 DB00904 Ondansetron Ondansetron is a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. SAL DB00936 Salicylic acid Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. SAN DB00259 Sulfanilamide Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. SAS DB00795 Sulfasalazine Sulfasalazine is an anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. SC2 DB06151 Acetylcysteine Acetylcysteine is a medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. SCK DB00202 Succinylcholine Succinylcholine is a depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. SCM DB00919 Spectinomycin Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of Neisseria gonorrhoeae. SFY DB00891 Sulfapyridine Sulfapyridine is a sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. SHH DB02546 Vorinostat Vorinostat is a histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. SMX DB01326 Cefamandole Cefamandole is a beta-lactam antibiotic used in the treatment of various infections caused by susceptible strains of bacteria, such as lower respiratory infections, urinary tract infections, skin infections, and bone and joint infections. SNL DB00421 Spironolactone Spironolactone is an aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia. SOR DB01638 Sorbitol Sorbitol is a product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. SPP DB00705 Delavirdine Delavirdine is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. SPR DB06145 Spiramycin Spiramycin is a macrolide antimicrobial agent used in the treatment of various bacterial infections. SRE DB01104 Sertraline Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. SRY DB01082 Streptomycin Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. STI DB00619 Imatinib Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. STR DB00396 Progesterone Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. STZ DB00428 Streptozocin Streptozocin is a nitrosourea antineoplastic agent used in the treatment of metastatic pancreatic islet cell carcinoma. SUE DB11575 Grazoprevir Grazoprevir is an antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. SUV DB09034 Suvorexant Suvorexant is a orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. SUZ DB00605 Sulindac Sulindac is an NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. SV6 DB05521 Telaprevir Telaprevir is an NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. T0R DB00539 Toremifene Toremifene is a first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers. T1C DB00560 Tigecycline Tigecycline is a glycylcycline antibiotic used to treat a number of susceptible bacterial infections. T22 DB06203 Alogliptin Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. T27 DB08864 Rilpivirine Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). T3 DB00279 Liothyronine Liothyronine is a thyroid hormone replacement therapy used to treat hypothyroidism, to suppress TSH, and to help in the diagnosis of hyperthyroidism. T44 DB00451 Levothyroxine Levothyroxine is a synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer. TA1 DB01229 Paclitaxel Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. TAC DB00759 Tetracycline Tetracycline is an antibiotic used to treat a wide variety of susceptible infections. TAZ DB01606 Tazobactam Tazobactam is a beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. TC9 DB01199 Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... TCI DB00470 Dronabinol Dronabinol is a synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. TCL DB08604 Triclosan Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew. TCW DB00323 Tolcapone Tolcapone is a catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease. TE4 DB09085 Tetracaine Tetracaine is a local anaesthetic agent used to induce local analgesia in the eyes and skin during medical procedures. TEI DB04854 Febuxostat Febuxostat is a xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol. TEP DB00277 Theophylline Theophylline is a xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. TES DB00624 Testosterone Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. TFP DB00831 Trifluoperazine Trifluoperazine is a phenothiazine used to treat depression, anxiety, and agitation. THA DB00382 Tacrine Tacrine is an anticholinesterase drug used for the management of Alzheimer's disease symptoms. THH DB11256 Levomefolic acid Levomefolic acid is a folate supplement used to prevent neural tube defects in pregnancy or folate deficiency. TIC DB00208 Ticlopidine Ticlopidine is a platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). TIM DB00373 Timolol Timolol is a non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. TIQ DB08816 Ticagrelor Ticagrelor is a P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. TJ7 DB12343 Temocillin Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. TKT DB11699 Tropisetron Tropisetron is a 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. TLF DB09216 Tolfenamic acid Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as... TLS DB00966 Telmisartan Telmisartan is an ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. TLT DB00500 Tolmetin Tolmetin is an NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis. TMG DB00730 Thiabendazole Thiabendazole is a benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. TMI DB04794 Bifonazole Bifonazole is an azole antifungal drug used to treat fungal skin infections, such as dermatomycosis. TMQ DB01157 Trimetrexate Trimetrexate is a folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. TNG DB00727 Nitroglycerin Nitroglycerin is a nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively. TOP DB00440 Trimethoprim Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. TOR DB00273 Topiramate Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. TOY DB00684 Tobramycin Tobramycin is an aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. TP0 DB00321 Amitriptyline Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. TPF DB00196 Fluconazole Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis. TPV DB00932 Tipranavir Tipranavir is a protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. TTC DB01030 Topotecan Topotecan is an antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer. TUA DB00860 Prednisolone Prednisolone is a glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. TXC DB00577 Valaciclovir Valaciclovir is an guanine nucleoside antiviral used to treat herpes exacerbations. TXL DB01248 Docetaxel Docetaxel is a taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. TYL DB00316 Acetaminophen Acetaminophen is an analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. TZN DB01162 Terazosin Terazosin is an alpha-1 adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia and management of hypertension. UAS DB00498 Phenindione An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.... UQA DB01174 Phenobarbital Phenobarbital is a long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. URF DB00544 Fluorouracil Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. V2H DB06410 Doxercalciferol Doxercalciferol is a synthetic vitamin D2 analog used to treat secondary hyperparathyroidism in patients with chronic kidney disease with or without therapy of dialysis. V6A DB11942 Selinexor Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. It is currently approved for the treatment of multiple myeloma, a cancer which forms from antibody-producing plasma cells.[L7117,L7120] This... V8D DB00292 Etomidate Etomidate is a short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. VDN DB00862 Vardenafil Vardenafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction. VGH DB08865 Crizotinib Crizotinib is a receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. VIA DB00203 Sildenafil Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction. VIS DB08828 Vismodegib Vismodegib is a hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. VLB DB00570 Vinblastine Vinblastine is a vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. VOR DB00582 Voriconazole Voriconazole is a triazole compound used to treat fungal infections. VPX DB09030 Vorapaxar Vorapaxar is a platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD). VX7 DB08820 Ivacaftor Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. W1P DB12243 Edaravone Edaravone is a free radical scavenger used to delay the progression of ALS. WJZ DB06823 Tiopronin Tiopronin is a thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. WPP DB00319 Piperacillin Piperacillin is a penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria. X0T DB00651 Dyphylline Dyphylline is a theophylline derivative used to treat asthma, bronchospasm, and COPD. X2N DB01263 Posaconazole Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. X8M DB00332 Ipratropium Ipratropium is an anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). X8Z DB01197 Captopril Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. XB7 DB00637 Astemizole Astemizole is a second generation antihistamine used to treat allergy symptoms. XIN DB09079 Nintedanib Nintedanib is a triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer. XPG DB00770 Alprostadil Alprostadil is a medication used to treat erectile dysfunction. XRA DB00457 Prazosin Prazosin is an alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. XT8 DB01607 Ticarcillin Ticarcillin is a beta lactam antibiotic used to treat a variety of infections in the body. Y00 DB00841 Dobutamine Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. YMX DB11986 Entrectinib Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019... YMZ DB00358 Mefloquine Mefloquine is an antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax. YNU DB00700 Eplerenone Eplerenone is an aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. YQM DB12329 Eravacycline Eravacycline is a tetracycline antibiotic used to treat complicated intra-abdominal infections. YTZ DB06147 Sulfathiazole Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination... YY3 DB09330 Osimertinib Osimertinib is a tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. Z80 DB00477 Chlorpromazine Chlorpromazine is a phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. ZD6 DB05294 Vandetanib Vandetanib is an antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. ZIO DB11442 Oleandomycin Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of Streptomyces antibioticus. ZIT DB00207 Azithromycin Azithromycin is a macrolide antibiotic used to treat a variety of bacterial infections. ZK5 DB00687 Fludrocortisone Fludrocortisone is a mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. ZLD DB00601 Linezolid Linezolid is an oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. ZLK DB00549 Zafirlukast Zafirlukast is a leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. ZMR DB00558 Zanamivir Zanamivir is a neuraminidase inhibitor used to treat influenza A and B. ZOL DB00399 Zoledronic acid Zoledronic acid is a bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. ZON DB00909 Zonisamide Zonisamide is a sulfonamide anticonvulsant used to treat partial seizures. ZOT DB09225 Zotepine Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. It has been used as an antipsychotic in Japan, India... ZPC DB00402 Eszopiclone Eszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.