Ligand ID: YMX

Drugbank ID:
Entrectinib
(DB11986)

Indication:
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019...


LIST OF BINDING INTERFACES for query 'YMX'

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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
5FTO_A_YMXA24025fto YMXEntrectinib
(DB11986) 		Homo sapiens ALK TYROSINE KINASE RECEPTOR PK_Tyr_Ser-Thr 21LEU A1122
GLY A1123
HIS A1124
PHE A1127
VAL A1130
ALA A1148
LYS A1150
LEU A1196
GLU A1197
LEU A1198
MET A1199
ALA A1200
GLY A1201
GLY A1202
ASP A1203
ARG A1253
ASN A1254
CYS A1255
LEU A1256
GLY A1269
ASP A1270
YMX A2402
5KVT_A_YMXA8015kvt YMXEntrectinib
(DB11986) 		Homo sapiens HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR PK_Tyr_Ser-Thr 22LEU A 516
GLY A 517
GLU A 518
PHE A 521
VAL A 524
ALA A 542
VAL A 573
PHE A 589
GLU A 590
TYR A 591
MET A 592
ARG A 593
HIS A 594
GLY A 595
ASP A 596
ARG A 599
ARG A 654
ASN A 655
CYS A 656
LEU A 657
GLY A 667
ASP A 668
YMX A 801
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details