Ligand ID: V6A

Drugbank ID:
Selinexor
(DB11942)

Indication:
Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound. It is currently approved for the treatment of multiple myeloma, a cancer which forms from antibody-producing plasma cells.[L7117,L7120] This...

LIST OF BINDING INTERFACES for query 'V6A'

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DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6XJS_C_V6AC1103	6xjs	V6A	Selinexor (DB11942)	Homo sapiens; saccharomyces cerevisiae	EXPORTIN-1	CRM1_C CRM1_repeat CRM1_repeat_2 CRM1_repeat_3 IBN_N Xpo1	15	ILE C 532 LEU C 536 CYS C 539 LYS C 548 VAL C 551 ALA C 552 ILE C 555 MET C 556 VAL C 559 PHE C 572 THR C 575 VAL C 576 LYS C 579 LEU C 580 PHE C 583	V6A C1103		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6XJS_C_V6AC1103","6xjs","V6A","Selinexor (DB11942)","Homo sapiens;saccharomyces cerevisiae","EXPORTIN-1","CRM1_C;CRM1_repeat;CRM1_repeat_2;CRM1_repeat_3;IBN_N;Xpo1",15,"ILE C 532;LEU C 536;CYS C 539;LYS C 548;VAL C 551;ALA C 552;ILE C 555;MET C 556;VAL C 559;PHE C 572;THR C 575;VAL C 576;LYS C 579;LEU C 580;PHE C 583","V6A C1103\r"]]