Ligand ID: TTC

Drugbank ID:
Topotecan
(DB01030)

Indication:
Topotecan is an antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.

LIST OF BINDING INTERFACES for query 'TTC'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
7NEZ_A_TTCA1201	7nez	TTC	Topotecan (DB01030)	Homo sapiens; mus musculus	ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2	ABC2_membrane ABC2_membrane_7 ABC_tran	19	VAL A 401 LEU A 405 PHE A 431 PHE B 432 THR B 435 ASN A 436 PHE A 439 PHE B 439 SER A 440 VAL A 442 SER A 443 LEU B 539 THR B 542 THR A 542 ILE B 543 VAL A 546 VAL B 546 MET A 549 MET B 549	TTC A1201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["7NEZ_A_TTCA1201","7nez","TTC","Topotecan (DB01030)","Homo sapiens;mus musculus","ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2","ABC2_membrane;ABC2_membrane_7;ABC_tran",19,"VAL A 401;LEU A 405;PHE A 431;PHE B 432;THR B 435;ASN A 436;PHE A 439;PHE B 439;SER A 440;VAL A 442;SER A 443;LEU B 539;THR B 542;THR A 542;ILE B 543;VAL A 546;VAL B 546;MET A 549;MET B 549","TTC A1201\r"]]