Results: Ligand

Ligand ID: TFP

Drugbank ID:
Trifluoperazine
(DB00831)

Indication:
Trifluoperazine is a phenothiazine used to treat depression, anxiety, and agitation.

LIST OF BINDING INTERFACES for query 'TFP'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1LIN_A_TFPA153	1lin	TFP	Trifluoperazine (DB00831)	Bos taurus	CALMODULIN	EF-hand_7	11	GLU A 11 PHE A 92 ILE A 100 LEU A 105 MET A 124 ILE A 125 GLU A 127 ALA A 128 VAL A 136 PHE A 141 MET A 144	TFP A 153
1LIN_A_TFPA154	1lin	TFP	Trifluoperazine (DB00831)	Bos taurus	CALMODULIN	EF-hand_7	11	GLU A 11 GLU A 14 ALA A 15 LEU A 18 MET A 109 GLU A 114 LYS A 115 LEU A 116 GLU A 120 GLU A 123 MET A 124	TFP A 154
1LIN_A_TFPA155	1lin	TFP	Trifluoperazine (DB00831)	Bos taurus	CALMODULIN	EF-hand_7	10	GLN A 8 GLU A 11 PHE A 12 ALA A 15 MET A 72 ARG A 74 PHE A 92 MET A 144 MET A 145 ALA A 147	TFP A 155
1LIN_A_TFPA156	1lin	TFP	Trifluoperazine (DB00831)	Bos taurus	CALMODULIN	EF-hand_7	10	PHE A 19 ILE A 27 LEU A 32 MET A 51 ILE A 52 GLU A 54 VAL A 55 ILE A 63 PHE A 68 MET A 71	TFP A 156
1WRK_A_TFPA202	1wrk	TFP	Trifluoperazine (DB00831)	Homo sapiens	TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES	EF-hand_8	15	GLU B 15 GLU B 19 PHE B 20 ALA B 23 LEU A 41 VAL A 44 MET A 45 LEU A 48 GLN A 50 GLU A 56 MET A 60 PHE A 77 MET A 80 MET A 81 SER A 84	TFP A 202
1WRK_A_TFPA204	1wrk	TFP	Trifluoperazine (DB00831)	Homo sapiens	TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES	EF-hand_8	11	PHE A 20 PHE B 20 PHE A 27 VAL A 44 LEU B 48 LEU A 48 PHE A 77 MET A 81 VAL A 82 SER A 84 MET A 85	TFP A 204
3KO0_A_TFPA201	3ko0	TFP	Trifluoperazine (DB00831)	Homo sapiens	PROTEIN S100-A4	S_100	14	SER A 44 PHE A 45 LEU A 46 GLY A 47 CYS A 81 ILE A 82 MET A 85 CYS A 86 PHE C 89 PHE A 89 PHE C 90 GLY C 92 PHE A 93 PHE C 93	TFP A 201
3KO0_A_TFPA202	3ko0	TFP	Trifluoperazine (DB00831)	Homo sapiens	PROTEIN S100-A4	S_100	14	GLU B 6 LEU B 9 ASP B 10 ASP D 10 SER D 14 LEU A 42 SER A 44 PHE A 45 ILE A 82 CYS A 86 PHE C 89 PHE A 89 PHE C 90 PHE A 90	TFP A 202
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1LIN_A_TFPA153","1lin","TFP","Trifluoperazine (DB00831)","Bos taurus","CALMODULIN","EF-hand_7",11,"GLU A  11;PHE A  92;ILE A 100;LEU A 105;MET A 124;ILE A 125;GLU A 127;ALA A 128;VAL A 136;PHE A 141;MET A 144","TFP A 153\r"],["1LIN_A_TFPA154","1lin","TFP","Trifluoperazine (DB00831)","Bos taurus","CALMODULIN","EF-hand_7",11,"GLU A  11;GLU A  14;ALA A  15;LEU A  18;MET A 109;GLU A 114;LYS A 115;LEU A 116;GLU A 120;GLU A 123;MET A 124","TFP A 154\r"],["1LIN_A_TFPA155","1lin","TFP","Trifluoperazine (DB00831)","Bos taurus","CALMODULIN","EF-hand_7",10,"GLN A   8;GLU A  11;PHE A  12;ALA A  15;MET A  72;ARG A  74;PHE A  92;MET A 144;MET A 145;ALA A 147","TFP A 155\r"],["1LIN_A_TFPA156","1lin","TFP","Trifluoperazine (DB00831)","Bos taurus","CALMODULIN","EF-hand_7",10,"PHE A  19;ILE A  27;LEU A  32;MET A  51;ILE A  52;GLU A  54;VAL A  55;ILE A  63;PHE A  68;MET A  71","TFP A 156\r"],["1WRK_A_TFPA202","1wrk","TFP","Trifluoperazine (DB00831)","Homo sapiens","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","EF-hand_8",15,"GLU B  15;GLU B  19;PHE B  20;ALA B  23;LEU A  41;VAL A  44;MET A  45;LEU A  48;GLN A  50;GLU A  56;MET A  60;PHE A  77;MET A  80;MET A  81;SER A  84","TFP A 202\r"],["1WRK_A_TFPA204","1wrk","TFP","Trifluoperazine (DB00831)","Homo sapiens","TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES","EF-hand_8",11,"PHE A  20;PHE B  20;PHE A  27;VAL A  44;LEU B  48;LEU A  48;PHE A  77;MET A  81;VAL A  82;SER A  84;MET A  85","TFP A 204\r"],["3KO0_A_TFPA201","3ko0","TFP","Trifluoperazine (DB00831)","Homo sapiens","PROTEIN S100-A4","S_100",14,"SER A  44;PHE A  45;LEU A  46;GLY A  47;CYS A  81;ILE A  82;MET A  85;CYS A  86;PHE C  89;PHE A  89;PHE C  90;GLY C  92;PHE A  93;PHE C  93","TFP A 201\r"],["3KO0_A_TFPA202","3ko0","TFP","Trifluoperazine (DB00831)","Homo sapiens","PROTEIN S100-A4","S_100",14,"GLU B   6;LEU B   9;ASP B  10;ASP D  10;SER D  14;LEU A  42;SER A  44;PHE A  45;ILE A  82;CYS A  86;PHE C  89;PHE A  89;PHE C  90;PHE A  90","TFP A 202\r"]]