Ligand ID: RIS

Drugbank ID:
Risedronic acid
(DB00884)

Indication:
Risedronic acid is a bisphosphonate used to treat osteoporosis and Paget's disease.

LIST OF BINDING INTERFACES for query 'RIS'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1RQJ_A_RISA901	1rqj	RIS	Risedronic acid (DB00884)	Escherichia coli	GERANYLTRANSTRANSFERASE	polyprenyl_synt	16	SER A 101 LEU A 102 ASP A 105 ASP A 106 ASP A 111 ARG A 116 MET A 175 GLN A 179 ASP A 182 LYS A 202 THR A 203 GLN A 241 ASP A 244 ASP A 248 LYS A 258 ASP A 263	RIS A 901		Details
1YHL_A_RISA1400	1yhl	RIS	Risedronic acid (DB00884)	Trypanosoma cruzi	FARNESYL PYROPHOSPHATE SYNTHASE	polyprenyl_synt	15	TYR A  94 LEU A  95 ASP A  98 ASP A  99 ASP A 102 ARG A 107 GLN A 167 ASP A 170 LYS A 207 THR A 208 TYR A 211 GLN A 247 ASP A 250 LYS A 264 ASP A 268	RIS A1400		Details
2O1O_A_RISA400	2o1o	RIS	Risedronic acid (DB00884)	Cryptosporidium parvum	PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE	polyprenyl_synt	12	ILE A 111 LEU A 112 ASP A 115 ASP A 119 ARG A 124 GLN A 184 LYS A 210 THR A 211 TYR A 214 GLN A 251 ASN A 254 ASP A 255	RIS A 400		Details
4RXD_A_RISA1404	4rxd	RIS	Risedronic acid (DB00884)	Trypanosoma brucei	FARNESYL PYROPHOSPHATE SYNTHASE	polyprenyl_synt	16	TYR A  99 LEU A 100 ASP A 103 ASP A 104 ASP A 107 ARG A 112 THR A 168 GLN A 172 LYS A 212 THR A 213 TYR A 216 GLN A 252 ASP A 255 ASP A 259 LYS A 269 ASP A 273	RIS A1404		Details
5CG5_A_RISA400	5cg5	RIS	Risedronic acid (DB00884)	Homo sapiens	FARNESYL PYROPHOSPHATE SYNTHASE	polyprenyl_synt	15	PHE A  99 LEU A 100 ASP A 103 ASP A 104 ASP A 107 ARG A 112 THR A 167 GLN A 171 LYS A 200 THR A 201 TYR A 204 GLN A 240 ASP A 243 LYS A 257 ASP A 261	RIS A 400		Details
7KJD_A_RISA405	7kjd	RIS	Risedronic acid (DB00884)	Streptomyces coelicolor	EPI-ISOZIZAENE SYNTHASE	Terpene_syn_C_2	14	PHE A  95 MET A  96 ASP A  99 TYR A 172 ARG A 194 THR A 197 PHE A 198 TRP A 203 ASN A 240 SER A 244 LYS A 247 GLU A 248 ARG A 338 TYR A 339	RIS A 405		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1RQJ_A_RISA901","1rqj","RIS","Risedronic acid (DB00884)","Escherichia coli","GERANYLTRANSTRANSFERASE","polyprenyl_synt",16,"SER A 101;LEU A 102;ASP A 105;ASP A 106;ASP A 111;ARG A 116;MET A 175;GLN A 179;ASP A 182;LYS A 202;THR A 203;GLN A 241;ASP A 244;ASP A 248;LYS A 258;ASP A 263","RIS A 901\r"],["1YHL_A_RISA1400","1yhl","RIS","Risedronic acid (DB00884)","Trypanosoma cruzi","FARNESYL PYROPHOSPHATE SYNTHASE","polyprenyl_synt",15,"TYR A 94;LEU A 95;ASP A 98;ASP A 99;ASP A 102;ARG A 107;GLN A 167;ASP A 170;LYS A 207;THR A 208;TYR A 211;GLN A 247;ASP A 250;LYS A 264;ASP A 268","RIS A1400\r"],["2O1O_A_RISA400","2o1o","RIS","Risedronic acid (DB00884)","Cryptosporidium parvum","PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE","polyprenyl_synt",12,"ILE A 111;LEU A 112;ASP A 115;ASP A 119;ARG A 124;GLN A 184;LYS A 210;THR A 211;TYR A 214;GLN A 251;ASN A 254;ASP A 255","RIS A 400\r"],["4RXD_A_RISA1404","4rxd","RIS","Risedronic acid (DB00884)","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","polyprenyl_synt",16,"TYR A 99;LEU A 100;ASP A 103;ASP A 104;ASP A 107;ARG A 112;THR A 168;GLN A 172;LYS A 212;THR A 213;TYR A 216;GLN A 252;ASP A 255;ASP A 259;LYS A 269;ASP A 273","RIS A1404\r"],["5CG5_A_RISA400","5cg5","RIS","Risedronic acid (DB00884)","Homo sapiens","FARNESYL PYROPHOSPHATE SYNTHASE","polyprenyl_synt",15,"PHE A 99;LEU A 100;ASP A 103;ASP A 104;ASP A 107;ARG A 112;THR A 167;GLN A 171;LYS A 200;THR A 201;TYR A 204;GLN A 240;ASP A 243;LYS A 257;ASP A 261","RIS A 400\r"],["7KJD_A_RISA405","7kjd","RIS","Risedronic acid (DB00884)","Streptomyces coelicolor","EPI-ISOZIZAENE SYNTHASE","Terpene_syn_C_2",14,"PHE A 95;MET A 96;ASP A 99;TYR A 172;ARG A 194;THR A 197;PHE A 198;TRP A 203;ASN A 240;SER A 244;LYS A 247;GLU A 248;ARG A 338;TYR A 339","RIS A 405\r"]]