Ligand ID: RAL

Drugbank ID:
Raloxifene
(DB00481)

Indication:
Raloxifene is a selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women.

LIST OF BINDING INTERFACES for query 'RAL'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1QKN_A_RALA600	1qkn	RAL	Raloxifene (DB00481)	Rattus norvegicus	ESTROGEN RECEPTOR BETA	Hormone_recep	22	MET A 250 LEU A 253 THR A 254 LEU A 256 ALA A 257 ASP A 258 GLU A 260 LEU A 261 TRP A 290 MET A 291 LEU A 294 MET A 295 LEU A 298 ARG A 301 PHE A 311 ILE A 328 ILE A 331 PHE A 332 LEU A 335 GLY A 427 HIS A 430 LEU A 431	RAL A 600		Details
2QXS_A_RALA600	2qxs	RAL	Raloxifene (DB00481)	Homo sapiens	ESTROGEN RECEPTOR	Hormone_recep	26	MET A 343 LEU A 346 THR A 347 LEU A 349 ALA A 350 ASP A 351 GLU A 353 LEU A 354 TRP A 383 LEU A 384 LEU A 387 MET A 388 LEU A 391 ARG A 394 PHE A 404 MET A 421 ILE A 424 LEU A 428 GLY A 521 HIS A 524 LEU A 525 ASN A 532 VAL A 533 VAL A 534 PRO A 535 LEU A 539	RAL A 600		Details
2Y05_A_RALA801	2y05	RAL	Raloxifene (DB00481)	Homo sapiens	PROSTAGLANDIN REDUCTASE 1	ADH_N_2 ADH_zinc_N	10	TYR A  49 VAL A  52 ALA A  53 ARG A  56 VAL B  77 ALA B  78 SER A  88 TYR A 245 VAL A 271 TYR A 273	RAL A 801		Details
2Y05_A_RALA802	2y05	RAL	Raloxifene (DB00481)	Homo sapiens	PROSTAGLANDIN REDUCTASE 1	ADH_N_2 ADH_zinc_N	11	ASN B  34 GLY B  35 SER B  74 LYS B  75 ASN B  76 VAL B  77 ASP B  98 LYS B 100 VAL A 271 TYR A 273 ARG A 274	RAL A 802		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1QKN_A_RALA600","1qkn","RAL","Raloxifene (DB00481)","Rattus norvegicus","ESTROGEN RECEPTOR BETA","Hormone_recep",22,"MET A 250;LEU A 253;THR A 254;LEU A 256;ALA A 257;ASP A 258;GLU A 260;LEU A 261;TRP A 290;MET A 291;LEU A 294;MET A 295;LEU A 298;ARG A 301;PHE A 311;ILE A 328;ILE A 331;PHE A 332;LEU A 335;GLY A 427;HIS A 430;LEU A 431","RAL A 600\r"],["2QXS_A_RALA600","2qxs","RAL","Raloxifene (DB00481)","Homo sapiens","ESTROGEN RECEPTOR","Hormone_recep",26,"MET A 343;LEU A 346;THR A 347;LEU A 349;ALA A 350;ASP A 351;GLU A 353;LEU A 354;TRP A 383;LEU A 384;LEU A 387;MET A 388;LEU A 391;ARG A 394;PHE A 404;MET A 421;ILE A 424;LEU A 428;GLY A 521;HIS A 524;LEU A 525;ASN A 532;VAL A 533;VAL A 534;PRO A 535;LEU A 539","RAL A 600\r"],["2Y05_A_RALA801","2y05","RAL","Raloxifene (DB00481)","Homo sapiens","PROSTAGLANDIN REDUCTASE 1","ADH_N_2;ADH_zinc_N",10,"TYR A 49;VAL A 52;ALA A 53;ARG A 56;VAL B 77;ALA B 78;SER A 88;TYR A 245;VAL A 271;TYR A 273","RAL A 801\r"],["2Y05_A_RALA802","2y05","RAL","Raloxifene (DB00481)","Homo sapiens","PROSTAGLANDIN REDUCTASE 1","ADH_N_2;ADH_zinc_N",11,"ASN B 34;GLY B 35;SER B 74;LYS B 75;ASN B 76;VAL B 77;ASP B 98;LYS B 100;VAL A 271;TYR A 273;ARG A 274","RAL A 802\r"]]