Ligand ID: PNX

Drugbank ID:
Pentoxifylline
(DB00806)

Indication:
Pentoxifylline is a methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.

LIST OF BINDING INTERFACES for query 'PNX'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2A3C_A_PNXA1434	2a3c	PNX	Pentoxifylline (DB00806)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	14	TYR A  48 TRP A  52 PHE A  76 GLY A 136 TRP A 137 THR A 138 ASP A 175 GLU A 177 ALA A 217 MET A 243 TYR A 245 ASP A 246 TYR A 299 TRP A 384	PNX A1434		Details
2A3C_A_PNXA1435	2a3c	PNX	Pentoxifylline (DB00806)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	10	TRP A 137 GLU A 177 TYR A 178 ASP A 246 ALA A 248 GLY A 249 SER A 250 PHE A 251 SER A 252 ARG A 301	PNX A1435		Details
3ARR_A_PNXA606	3arr	PNX	Pentoxifylline (DB00806)	Vibrio harveyi	CHITINASE A	Glyco_hydro_18	11	TRP A 275 PHE A 316 VAL A 366 GLY A 367 ASP A 369 LYS A 370 ASP A 392 PHE A 393 TRP A 397 TYR A 435 ARG A 463	PNX A 606		Details
3ARR_A_PNXA607	3arr	PNX	Pentoxifylline (DB00806)	Vibrio harveyi	CHITINASE A	Glyco_hydro_18	9	TRP A 168 PHE A 192 VAL A 205 SER A 209 HIS A 228 TRP A 275 THR A 276 LEU A 277 TRP A 570	PNX A 607		Details
3TVX_A_PNXA902	3tvx	PNX	Pentoxifylline (DB00806)	Homo sapiens	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A	PDEase_I	14	TYR A 371 MET A 485 LEU A 531 ASN A 533 PRO A 534 TYR A 541 TRP A 544 THR A 545 ILE A 548 PHE A 552 MET A 569 SER A 580 GLN A 581 PHE A 584	PNX A 902		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2A3C_A_PNXA1434","2a3c","PNX","Pentoxifylline (DB00806)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",14,"TYR A 48;TRP A 52;PHE A 76;GLY A 136;TRP A 137;THR A 138;ASP A 175;GLU A 177;ALA A 217;MET A 243;TYR A 245;ASP A 246;TYR A 299;TRP A 384","PNX A1434\r"],["2A3C_A_PNXA1435","2a3c","PNX","Pentoxifylline (DB00806)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",10,"TRP A 137;GLU A 177;TYR A 178;ASP A 246;ALA A 248;GLY A 249;SER A 250;PHE A 251;SER A 252;ARG A 301","PNX A1435\r"],["3ARR_A_PNXA606","3arr","PNX","Pentoxifylline (DB00806)","Vibrio harveyi","CHITINASE A","Glyco_hydro_18",11,"TRP A 275;PHE A 316;VAL A 366;GLY A 367;ASP A 369;LYS A 370;ASP A 392;PHE A 393;TRP A 397;TYR A 435;ARG A 463","PNX A 606\r"],["3ARR_A_PNXA607","3arr","PNX","Pentoxifylline (DB00806)","Vibrio harveyi","CHITINASE A","Glyco_hydro_18",9,"TRP A 168;PHE A 192;VAL A 205;SER A 209;HIS A 228;TRP A 275;THR A 276;LEU A 277;TRP A 570","PNX A 607\r"],["3TVX_A_PNXA902","3tvx","PNX","Pentoxifylline (DB00806)","Homo sapiens","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4A","PDEase_I",14,"TYR A 371;MET A 485;LEU A 531;ASN A 533;PRO A 534;TYR A 541;TRP A 544;THR A 545;ILE A 548;PHE A 552;MET A 569;SER A 580;GLN A 581;PHE A 584","PNX A 902\r"]]