Ligand ID: NBV

Drugbank ID:
Miglustat
(DB00419)

Indication:
Miglustat is a glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.

LIST OF BINDING INTERFACES for query 'NBV'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2V3D_A_NBVA1503	2v3d	NBV	Miglustat (DB00419)	Homo sapiens	GLUCOSYLCERAMIDASE	Glyco_hydro_30 Glyco_hydro_30C	15	ASP A 127 PHE A 128 TRP A 179 ASN A 234 GLU A 235 PHE A 246 GLN A 284 HIS A 311 TYR A 313 GLU A 340 CYS A 342 SER A 345 TRP A 381 ASN A 396 VAL A 398	NBV A1503		Details
5IEF_A_NBVA1005	5ief	NBV	Miglustat (DB00419)	Mus musculus	NEUTRAL ALPHA-GLUCOSIDASE AB	Gal_mutarotas_2 Glyco_hydro_31	17	ASP A 305 TRP A 423 ASP A 451 ILE A 452 ILE A 488 TRP A 525 TRP A 562 ASP A 564 MET A 565 PHE A 571 ARG A 624 TRP A 637 ASP A 640 ASP A 669 PHE A 673 ARG A 696 HIS A 698	NBV A1005		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2V3D_A_NBVA1503","2v3d","NBV","Miglustat (DB00419)","Homo sapiens","GLUCOSYLCERAMIDASE","Glyco_hydro_30;Glyco_hydro_30C",15,"ASP A 127;PHE A 128;TRP A 179;ASN A 234;GLU A 235;PHE A 246;GLN A 284;HIS A 311;TYR A 313;GLU A 340;CYS A 342;SER A 345;TRP A 381;ASN A 396;VAL A 398","NBV A1503\r"],["5IEF_A_NBVA1005","5ief","NBV","Miglustat (DB00419)","Mus musculus","NEUTRAL ALPHA-GLUCOSIDASE AB","Gal_mutarotas_2;Glyco_hydro_31",17,"ASP A 305;TRP A 423;ASP A 451;ILE A 452;ILE A 488;TRP A 525;TRP A 562;ASP A 564;MET A 565;PHE A 571;ARG A 624;TRP A 637;ASP A 640;ASP A 669;PHE A 673;ARG A 696;HIS A 698","NBV A1005\r"]]