Results: Ligand

Ligand ID: ISZ

Drugbank ID:
Isoniazid
(DB00951)

Indication:
Isoniazid is an antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.

LIST OF BINDING INTERFACES for query 'ISZ'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1W6F_A_ISZA1276	1w6f	ISZ	Isoniazid (DB00951)	Mycobacterium smegmatis	ARYLAMINE N-ACETYLTRANSFERASE	Acetyltransf_2	11	PHE A 38 TYR A 69 CYS A 70 TYR A 71 VAL A 95 THR A 109 HIS A 110 GLY A 129 PHE A 130 VAL A 196 PHE A 204	ISZ A1276
1XR3_A_ISZA263	1xr3	ISZ	Isoniazid (DB00951)	Streptomyces coelicolor	ACTINORHODIN POLYKETIDE KETOREDUCTASE	adh_short	9	SER A 144 THR A 145 GLY A 146 GLN A 149 VAL A 151 TYR A 157 GLY A 188 PHE A 189 LEU A 258	ISZ A 263
2V2E_A_ISZA1296	2v2e	ISZ	Isoniazid (DB00951)	Saccharomyces cerevisiae	CYTOCHROME C PEROXIDASE	peroxidase	9	ARG A 48 TRP A 51 HIS A 52 SER A 81 LEU A 144 PRO A 145 ASP A 146 ALA A 147 SER A 185	ISZ A1296
2VCN_A_ISZA1254	2vcn	ISZ	Isoniazid (DB00951)	Glycine max	ASCORBATE PEROXIDASE	peroxidase	9	ARG A 38 ALA A 41 HIS A 42 GLY A 45 LEU A 131 PRO A 132 PHE A 145 MET A 149 HIS A 163	ISZ A1254
2VCN_A_ISZA1255	2vcn	ISZ	Isoniazid (DB00951)	Glycine max	ASCORBATE PEROXIDASE	peroxidase	7	LYS A 30 ARG A 31 CYS A 32 LEU A 35 ILE A 76 LEU A 80 ARG A 172	ISZ A1255
2VCN_A_ISZA1256	2vcn	ISZ	Isoniazid (DB00951)	Glycine max	ASCORBATE PEROXIDASE	peroxidase	10	ARG A 38 HIS A 42 SER A 69 ALA A 70 ASN A 72 PRO A 132 ASP A 133 ALA A 134 ARG A 172 SER A 173	ISZ A1256
3I6N_A_ISZA607	3i6n	ISZ	Isoniazid (DB00951)	Bos taurus	LACTOPEROXIDASE	An_peroxidase	8	GLN A 105 HIS A 109 ARG A 255 GLU A 258 PHE A 381 PHE A 422 GLN A 423 PRO A 424	ISZ A 607
3U72_A_ISZA4611	3u72	ISZ	Isoniazid (DB00951)	Bos taurus	LACTOTRANSFERRIN	Transferrin	8	THR A 430 GLU A 431 GLY A 432 VAL A 591 ALA A 592 PRO A 593 ASN A 594 TYR A 660	ISZ A4611
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1W6F_A_ISZA1276","1w6f","ISZ","Isoniazid (DB00951)","Mycobacterium smegmatis","ARYLAMINE N-ACETYLTRANSFERASE","Acetyltransf_2",11,"PHE A  38;TYR A  69;CYS A  70;TYR A  71;VAL A  95;THR A 109;HIS A 110;GLY A 129;PHE A 130;VAL A 196;PHE A 204","ISZ A1276\r"],["1XR3_A_ISZA263","1xr3","ISZ","Isoniazid (DB00951)","Streptomyces coelicolor","ACTINORHODIN POLYKETIDE KETOREDUCTASE","adh_short",9,"SER A 144;THR A 145;GLY A 146;GLN A 149;VAL A 151;TYR A 157;GLY A 188;PHE A 189;LEU A 258","ISZ A 263\r"],["2V2E_A_ISZA1296","2v2e","ISZ","Isoniazid (DB00951)","Saccharomyces cerevisiae","CYTOCHROME C PEROXIDASE","peroxidase",9,"ARG A  48;TRP A  51;HIS A  52;SER A  81;LEU A 144;PRO A 145;ASP A 146;ALA A 147;SER A 185","ISZ A1296\r"],["2VCN_A_ISZA1254","2vcn","ISZ","Isoniazid (DB00951)","Glycine max","ASCORBATE PEROXIDASE","peroxidase",9,"ARG A  38;ALA A  41;HIS A  42;GLY A  45;LEU A 131;PRO A 132;PHE A 145;MET A 149;HIS A 163","ISZ A1254\r"],["2VCN_A_ISZA1255","2vcn","ISZ","Isoniazid (DB00951)","Glycine max","ASCORBATE PEROXIDASE","peroxidase",7,"LYS A  30;ARG A  31;CYS A  32;LEU A  35;ILE A  76;LEU A  80;ARG A 172","ISZ A1255\r"],["2VCN_A_ISZA1256","2vcn","ISZ","Isoniazid (DB00951)","Glycine max","ASCORBATE PEROXIDASE","peroxidase",10,"ARG A  38;HIS A  42;SER A  69;ALA A  70;ASN A  72;PRO A 132;ASP A 133;ALA A 134;ARG A 172;SER A 173","ISZ A1256\r"],["3I6N_A_ISZA607","3i6n","ISZ","Isoniazid (DB00951)","Bos taurus","LACTOPEROXIDASE","An_peroxidase",8,"GLN A 105;HIS A 109;ARG A 255;GLU A 258;PHE A 381;PHE A 422;GLN A 423;PRO A 424","ISZ A 607\r"],["3U72_A_ISZA4611","3u72","ISZ","Isoniazid (DB00951)","Bos taurus","LACTOTRANSFERRIN","Transferrin",8,"THR A 430;GLU A 431;GLY A 432;VAL A 591;ALA A 592;PRO A 593;ASN A 594;TYR A 660","ISZ A4611\r"]]