Ligand ID: HY0

Drugbank ID:
Hygromycin b
(DB11520)

Indication:
Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus which kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis.

LIST OF BINDING INTERFACES for query 'HY0'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3W0O_A_HY0A402	3w0o	HY0	Hygromycin b (DB11520)	Escherichia coli	HYGROMYCIN-B 4-O-KINASE	APH	16	GLN A 101 ASP A 198 PHE A 199 SER A 201 ASN A 202 ASN A 203 ASP A 216 SER A 218 GLU A 219 ASN A 231 TRP A 235 TRP A 238 LEU A 239 MET A 242 GLN A 273 ASP A 285	HY0 A 402		Details
4XCB_A_HY0A303	4xcb	HY0	Hygromycin b (DB11520)	Streptomyces hygroscopicus subsp. hygroscopicus	OXIDASE/HYDROXYLASE	PhyH	17	PHE A  46 ARG A  51 GLU A  87 TYR A  89 LEU A  99 TYR A 100 HIS A 102 TYR A 135 LYS A 137 GLU A 202 TRP A 232 GLU A 234 TYR A 247 ASP A 249 VAL A 252 GLU A 254 ASP A 255	HY0 A 303		Details
6IY9_A_HY0A401	6iy9	HY0	Hygromycin b (DB11520)	Streptomyces hygroscopicus	HYGROMYCIN-B 7''-O-KINASE	APH	16	THR A  54 HIS A  72 TRP A  73 CYS A  74 GLU A  77 SER A  78 LEU A 175 ASP A 223 HIS A 225 THR A 245 ASP A 246 TYR A 248 ASP A 298 PHE A 299 GLU A 300 GLU A 303	HY0 A 401		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3W0O_A_HY0A402","3w0o","HY0","Hygromycin b (DB11520)","Escherichia coli","HYGROMYCIN-B 4-O-KINASE","APH",16,"GLN A 101;ASP A 198;PHE A 199;SER A 201;ASN A 202;ASN A 203;ASP A 216;SER A 218;GLU A 219;ASN A 231;TRP A 235;TRP A 238;LEU A 239;MET A 242;GLN A 273;ASP A 285","HY0 A 402\r"],["4XCB_A_HY0A303","4xcb","HY0","Hygromycin b (DB11520)","Streptomyces hygroscopicus subsp. hygroscopicus","OXIDASE\/HYDROXYLASE","PhyH",17,"PHE A 46;ARG A 51;GLU A 87;TYR A 89;LEU A 99;TYR A 100;HIS A 102;TYR A 135;LYS A 137;GLU A 202;TRP A 232;GLU A 234;TYR A 247;ASP A 249;VAL A 252;GLU A 254;ASP A 255","HY0 A 303\r"],["6IY9_A_HY0A401","6iy9","HY0","Hygromycin b (DB11520)","Streptomyces hygroscopicus","HYGROMYCIN-B 7''-O-KINASE","APH",16,"THR A 54;HIS A 72;TRP A 73;CYS A 74;GLU A 77;SER A 78;LEU A 175;ASP A 223;HIS A 225;THR A 245;ASP A 246;TYR A 248;ASP A 298;PHE A 299;GLU A 300;GLU A 303","HY0 A 401\r"]]