Ligand ID: FIT

Drugbank ID:
Finasteride
(DB01216)

Indication:
Finasteride is an antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.

LIST OF BINDING INTERFACES for query 'FIT'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3G1R_B_FITB327	3g1r	FIT	Finasteride (DB01216)	Homo sapiens	3-OXO-5-BETA-STEROID 4-DEHYDROGENASE	Aldo_ket_red	13	TYR B  26 ILE B  57 TYR B  58 LYS B  87 TRP B  89 GLU B 120 TYR B 132 ARG B 134 TRP B 140 TRP B 230 LEU B 311 MET B 313 TRP B 314	FIT B 327		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3G1R_B_FITB327","3g1r","FIT","Finasteride (DB01216)","Homo sapiens","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","Aldo_ket_red",13,"TYR B 26;ILE B 57;TYR B 58;LYS B 87;TRP B 89;GLU B 120;TYR B 132;ARG B 134;TRP B 140;TRP B 230;LEU B 311;MET B 313;TRP B 314","FIT B 327\r"]]