Results: Ligand

Ligand ID: CLT

Drugbank ID:
Phenylbutyric acid
(DB06819)

Indication:
Phenylbutyric acid is an agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.

LIST OF BINDING INTERFACES for query 'CLT'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2AY7_B_CLTB414	2ay7	CLT	Phenylbutyric acid (DB06819)	Paracoccus denitrificans	AROMATIC AMINO ACID AMINOTRANSFERASE	Aminotran_1_2	16	ASP B 15 ILE B 17 LEU B 18 VAL B 37 GLY B 38 TYR A 70 THR B 109 TRP B 140 ASN B 142 ASN B 194 TYR B 225 LYS B 258 SER A 296 PHE A 297 PHE B 360 ARG B 386	CLT B 414
3TZ5_A_CLTA392	3tz5	CLT	Phenylbutyric acid (DB06819)	Rattus norvegicus	[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL	BCDHK_Adom3 HATPase_c	13	LEU A 68 ILE A 72 TYR A 99 LEU A 106 VAL A 125 LEU A 128 LEU A 129 HIS A 132 VAL A 135 ARG A 167 ILE A 170 ARG A 171 ALA A 174	CLT A 392
5VNL_B_CLTB1102	5vnl	CLT	Phenylbutyric acid (DB06819)	Homo sapiens; mus musculus	PROTEIN TRANSPORT PROTEIN SEC24A	Gelsolin Sec23_BS Sec23_helical Sec23_trunk zf-Sec23_Sec24	10	ARG B 430 TYR B 437 TYR B 496 VAL B 748 ARG B 750 ARG B 752 ALA B 806 LEU B 807 LEU B 808 ILE B 818	CLT B1102
5YOQ_A_CLTA601	5yoq	CLT	Phenylbutyric acid (DB06819)	Homo sapiens	SERUM ALBUMIN	Serum_albumin	15	LEU A 387 ILE A 388 ASN A 391 CYS A 392 PHE A 403 LEU A 407 ARG A 410 TYR A 411 LYS A 414 LEU A 430 VAL A 433 GLY A 434 CYS A 438 LEU A 453 SER A 489	CLT A 601
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2AY7_B_CLTB414","2ay7","CLT","Phenylbutyric acid (DB06819)","Paracoccus denitrificans","AROMATIC AMINO ACID AMINOTRANSFERASE","Aminotran_1_2",16,"ASP B  15;ILE B  17;LEU B  18;VAL B  37;GLY B  38;TYR A  70;THR B 109;TRP B 140;ASN B 142;ASN B 194;TYR B 225;LYS B 258;SER A 296;PHE A 297;PHE B 360;ARG B 386","CLT B 414\r"],["3TZ5_A_CLTA392","3tz5","CLT","Phenylbutyric acid (DB06819)","Rattus norvegicus","[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL","BCDHK_Adom3;HATPase_c",13,"LEU A  68;ILE A  72;TYR A  99;LEU A 106;VAL A 125;LEU A 128;LEU A 129;HIS A 132;VAL A 135;ARG A 167;ILE A 170;ARG A 171;ALA A 174","CLT A 392\r"],["5VNL_B_CLTB1102","5vnl","CLT","Phenylbutyric acid (DB06819)","Homo sapiens;mus musculus","PROTEIN TRANSPORT PROTEIN SEC24A","Gelsolin;Sec23_BS;Sec23_helical;Sec23_trunk;zf-Sec23_Sec24",10,"ARG B 430;TYR B 437;TYR B 496;VAL B 748;ARG B 750;ARG B 752;ALA B 806;LEU B 807;LEU B 808;ILE B 818","CLT B1102\r"],["5YOQ_A_CLTA601","5yoq","CLT","Phenylbutyric acid (DB06819)","Homo sapiens","SERUM ALBUMIN","Serum_albumin",15,"LEU A 387;ILE A 388;ASN A 391;CYS A 392;PHE A 403;LEU A 407;ARG A 410;TYR A 411;LYS A 414;LEU A 430;VAL A 433;GLY A 434;CYS A 438;LEU A 453;SER A 489","CLT A 601\r"]]