Ligand ID: CIA

Drugbank ID:
Tadalafil
(DB00820)

Indication:
Tadalafil is a phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.

LIST OF BINDING INTERFACES for query 'CIA'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1XOZ_A_CIAA501	1xoz	CIA	Tadalafil (DB00820)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PDEase_I	16	TYR A 612 LEU A 725 ALA A 767 ILE A 768 GLN A 775 ILE A 778 ALA A 779 VAL A 782 ALA A 783 PHE A 786 PHE A 787 LEU A 804 ILE A 813 MET A 816 GLN A 817 PHE A 820	CIA A 501		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1XOZ_A_CIAA501","1xoz","CIA","Tadalafil (DB00820)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PDEase_I",16,"TYR A 612;LEU A 725;ALA A 767;ILE A 768;GLN A 775;ILE A 778;ALA A 779;VAL A 782;ALA A 783;PHE A 786;PHE A 787;LEU A 804;ILE A 813;MET A 816;GLN A 817;PHE A 820","CIA A 501\r"]]