Ligand ID: C6F

Drugbank ID:
Gilteritinib
(DB12141)

Indication:
Gilteritinib is an AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.

LIST OF BINDING INTERFACES for query 'C6F'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6JQR_A_C6FA1001	6jqr	C6F	Gilteritinib (DB12141)	NA	RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3	PK_Tyr_Ser-Thr	16	LEU A 616 GLY A 617 VAL A 624 ALA A 642 VAL A 675 GLU A 692 TYR A 693 CYS A 694 CYS A 695 TYR A 696 GLY A 697 ASP A 698 LEU A 818 CYS A 828 ASP A 829 PHE A 830	C6F A1001		Details
7AB1_A_C6FA901	7ab1	C6F	Gilteritinib (DB12141)	Homo sapiens	TYROSINE-PROTEIN KINASE MER	PK_Tyr_Ser-Thr	17	LEU A 593 VAL A 601 ALA A 617 LYS A 619 ILE A 650 LEU A 671 PRO A 672 PHE A 673 MET A 674 LYS A 675 GLY A 677 ASP A 678 TYR A 685 ARG A 727 MET A 730 ALA A 740 ASP A 741	C6F A 901		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6JQR_A_C6FA1001","6jqr","C6F","Gilteritinib (DB12141)","NA","RECEPTOR-TYPE TYROSINE-PROTEIN KINASE FLT3","PK_Tyr_Ser-Thr",16,"LEU A 616;GLY A 617;VAL A 624;ALA A 642;VAL A 675;GLU A 692;TYR A 693;CYS A 694;CYS A 695;TYR A 696;GLY A 697;ASP A 698;LEU A 818;CYS A 828;ASP A 829;PHE A 830","C6F A1001\r"],["7AB1_A_C6FA901","7ab1","C6F","Gilteritinib (DB12141)","Homo sapiens","TYROSINE-PROTEIN KINASE MER","PK_Tyr_Ser-Thr",17,"LEU A 593;VAL A 601;ALA A 617;LYS A 619;ILE A 650;LEU A 671;PRO A 672;PHE A 673;MET A 674;LYS A 675;GLY A 677;ASP A 678;TYR A 685;ARG A 727;MET A 730;ALA A 740;ASP A 741","C6F A 901\r"]]