Ligand ID: 9PL

Drugbank ID:
Pilocarpine
(DB01085)


Indication:
Pilocarpine is a muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy.


LIST OF BINDING INTERFACES for query '9PL'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
3T3Q_A_9PLA5013t3q 9PLPilocarpine
(DB01085)
Homo sapiens CYTOCHROME P450 2A6 p450 12PHE A 107
PHE A 111
VAL A 117
PHE A 118
PHE A 209
ASN A 297
PHE A 300
ALA A 301
THR A 305
ILE A 366
LEU A 370
PHE A 480
9PL A 501
3T3Z_A_9PLA5013t3z 9PLPilocarpine
(DB01085)
Homo sapiens CYTOCHROME P450 2E1 p450 12LEU A 103
PHE A 106
PHE A 116
PHE A 207
LEU A 210
PHE A 298
ALA A 299
GLU A 302
THR A 303
VAL A 364
LEU A 368
PHE A 478
9PL A 501
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details