Ligand ID: 7HP

Drugbank ID:
Allopurinol
(DB00437)

Indication:
Allopurinol is a xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.

LIST OF BINDING INTERFACES for query '7HP'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1I0L_A_7HPA800	1i0l	7HP	Allopurinol (DB00437)	Trypanosoma cruzi	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	Pribosyltran	8	ILE A 113 ASN A 115 LYS A 143 ALA A 163 PHE A 164 VAL A 165 LEU A 170 ASP A 171	7HP A 800		Details
1PVS_A_7HPA800	1pvs	7HP	Allopurinol (DB00437)	Escherichia coli	DNA-3-METHYLADENINE GLYCOSYLASE II	AlkA_N HhH-GPD	8	GLY A 123 GLN A 124 LEU A 125 VAL A 126 TRP A 218 ASP A 237 ASP A 238 TYR A 239	7HP A 800		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1I0L_A_7HPA800","1i0l","7HP","Allopurinol (DB00437)","Trypanosoma cruzi","HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE","Pribosyltran",8,"ILE A 113;ASN A 115;LYS A 143;ALA A 163;PHE A 164;VAL A 165;LEU A 170;ASP A 171","7HP A 800\r"],["1PVS_A_7HPA800","1pvs","7HP","Allopurinol (DB00437)","Escherichia coli","DNA-3-METHYLADENINE GLYCOSYLASE II","AlkA_N;HhH-GPD",8,"GLY A 123;GLN A 124;LEU A 125;VAL A 126;TRP A 218;ASP A 237;ASP A 238;TYR A 239","7HP A 800\r"]]