Ligand ID: 715

Drugbank ID:
Sitagliptin
(DB01261)

Indication:
Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.

LIST OF BINDING INTERFACES for query '715'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1X70_A_715A801	1x70	715	Sitagliptin (DB01261)	Homo sapiens	DIPEPTIDYL PEPTIDASE IV	DPPIV_N Peptidase_S9	18	ARG A 125 GLU A 205 GLU A 206 VAL A 207 PHE A 208 SER A 209 PHE A 357 ARG A 358 TYR A 547 SER A 630 TYR A 631 VAL A 656 TRP A 659 TYR A 662 TYR A 666 ASN A 710 VAL A 711 HIS A 740	715 A 801		Details
4FFW_A_715A801	4ffw	715	Sitagliptin (DB01261)	Rattus norvegicus; mus musculus	DIPEPTIDYL PEPTIDASE 4	DPPIV_N Peptidase_S9	18	ARG A 123 GLU A 203 GLU A 204 ILE A 205 PHE A 206 GLY A 207 PHE A 355 ARG A 356 TYR A 548 SER A 631 TYR A 632 VAL A 657 TRP A 660 TYR A 663 TYR A 667 ASN A 711 VAL A 712 HIS A 741	715 A 801		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1X70_A_715A801","1x70","715","Sitagliptin (DB01261)","Homo sapiens","DIPEPTIDYL PEPTIDASE IV","DPPIV_N;Peptidase_S9",18,"ARG A 125;GLU A 205;GLU A 206;VAL A 207;PHE A 208;SER A 209;PHE A 357;ARG A 358;TYR A 547;SER A 630;TYR A 631;VAL A 656;TRP A 659;TYR A 662;TYR A 666;ASN A 710;VAL A 711;HIS A 740","715 A 801\r"],["4FFW_A_715A801","4ffw","715","Sitagliptin (DB01261)","Rattus norvegicus;mus musculus","DIPEPTIDYL PEPTIDASE 4","DPPIV_N;Peptidase_S9",18,"ARG A 123;GLU A 203;GLU A 204;ILE A 205;PHE A 206;GLY A 207;PHE A 355;ARG A 356;TYR A 548;SER A 631;TYR A 632;VAL A 657;TRP A 660;TYR A 663;TYR A 667;ASN A 711;VAL A 712;HIS A 741","715 A 801\r"]]