Ligand ID: 6V8

Drugbank ID:
Ixazomib
(DB09570)

Indication:
Ixazomib is a monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.


LIST OF BINDING INTERFACES for query '6V8'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
5LF7_H_6V8H3055lf7 6V8Ixazomib
(DB09570) 		Homo sapiens PROTEASOME SUBUNIT BETA TYPE-3;
PROTEASOME SUBUNIT BETA TYPE-7 		Pr_beta_C
Proteasome 		18THR H   2
ARG H  20
ALA H  21
THR H  22
GLU H  23
ALA H  28
CYS H  32
LYS H  34
GLY H  46
ALA H  47
GLY H  48
THR H  49
ALA H  50
THR H  53
GLU I 105
ASP I 124
LEU I 125
GLY H 169
6V8 H 305
5LF7_K_6V8K3055lf7 6V8Ixazomib
(DB09570) 		Homo sapiens PROTEASOME SUBUNIT BETA TYPE-1;
PROTEASOME SUBUNIT BETA TYPE-5 		Proteasome 16THR K   2
ARG K  20
ALA K  21
THR K  22
ALA K  23
ALA K  28
VAL K  32
LYS K  34
MET K  46
ALA K  47
GLY K  48
GLY K  49
ALA K  50
ASP L 125
PRO L 126
TYR K 170
6V8 K 305
5LF7_N_6V8N3055lf7 6V8Ixazomib
(DB09570) 		Homo sapiens PROTEASOME SUBUNIT BETA TYPE-6;
PROTEASOME SUBUNIT BETA TYPE-7 		Pr_beta_C 17THR N   2
ARG N  20
THR N  21
THR N  22
THR N  23
ALA N  28
THR N  32
LYS N  34
ARG N  46
SER N  47
GLY N  48
SER N  49
ALA N  50
THR N  53
TYR H 115
SER H 119
SER N 170
6V8 N 305
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details