Ligand ID: 69Q

Drugbank ID:
Enasidenib
(DB13874)

Indication:
Enasidenib is an isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.

LIST OF BINDING INTERFACES for query '69Q'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5I96_B_69QB502	5i96	69Q	Enasidenib (DB13874)	Homo sapiens	ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL	Iso_dh	29	LEU A 160 LEU B 160 VAL B 161 TRP A 164 TRP B 164 ILE B 168 ILE B 170 ILE B 290 ILE A 290 VAL A 294 VAL B 294 VAL A 297 VAL B 297 LEU A 298 LEU B 298 TRP A 306 TRP B 306 TYR B 311 TYR A 311 ASP A 312 ASP B 312 VAL B 315 VAL A 315 GLN B 316 GLN A 316 ILE B 319 ILE A 319 LEU B 320 LEU A 320	69Q B 502		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5I96_B_69QB502","5i96","69Q","Enasidenib (DB13874)","Homo sapiens","ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL","Iso_dh",29,"LEU A 160;LEU B 160;VAL B 161;TRP A 164;TRP B 164;ILE B 168;ILE B 170;ILE B 290;ILE A 290;VAL A 294;VAL B 294;VAL A 297;VAL B 297;LEU A 298;LEU B 298;TRP A 306;TRP B 306;TYR B 311;TYR A 311;ASP A 312;ASP B 312;VAL B 315;VAL A 315;GLN B 316;GLN A 316;ILE B 319;ILE A 319;LEU B 320;LEU A 320","69Q B 502\r"]]