Ligand ID: 3EW

Drugbank ID:
Selumetinib
(DB11689)

Indication:
Selumetinib is a MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN).

LIST OF BINDING INTERFACES for query '3EW'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4U7Z_A_3EWA502	4u7z	3EW	Selumetinib (DB11689)	Homo sapiens	DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1	Pkinase	19	GLY A  77 ASN A  78 GLY A  79 GLY A  80 LYS A  97 ILE A  99 LEU A 115 LEU A 118 VAL A 127 ILE A 141 MET A 143 CYS A 207 ASP A 208 PHE A 209 GLY A 210 VAL A 211 SER A 212 LEU A 215 ILE A 216	3EW A 502		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4U7Z_A_3EWA502","4u7z","3EW","Selumetinib (DB11689)","Homo sapiens","DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1","Pkinase",19,"GLY A 77;ASN A 78;GLY A 79;GLY A 80;LYS A 97;ILE A 99;LEU A 115;LEU A 118;VAL A 127;ILE A 141;MET A 143;CYS A 207;ASP A 208;PHE A 209;GLY A 210;VAL A 211;SER A 212;LEU A 215;ILE A 216","3EW A 502\r"]]