Ligand ID: 377

Drugbank ID:
Memantine
(DB01043)

Indication:
Memantine is an NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's.

LIST OF BINDING INTERFACES for query '377'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4TWD_A_377A401	4twd	377	Memantine (DB01043)	Dickeya chrysanthemi	CYS-LOOP LIGAND-GATED ION CHANNEL	NA	11	TYR E  38 GLU A  77 ILE A  79 ARG E  91 ASN E 103 GLU A 131 PRO A 132 PHE A 133 TYR A 175 LEU A 178 PHE A 188	377 A 401		Details
4TWD_A_377A402	4twd	377	Memantine (DB01043)	Dickeya chrysanthemi	CYS-LOOP LIGAND-GATED ION CHANNEL	NA	11	LEU E 240 ALA D 244 ALA C 244 ALA B 244 ALA E 244 ALA A 244 SER B 247 SER E 247 SER A 247 SER C 247 SER D 247	377 A 402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4TWD_A_377A401","4twd","377","Memantine (DB01043)","Dickeya chrysanthemi","CYS-LOOP LIGAND-GATED ION CHANNEL","NA",11,"TYR E 38;GLU A 77;ILE A 79;ARG E 91;ASN E 103;GLU A 131;PRO A 132;PHE A 133;TYR A 175;LEU A 178;PHE A 188","377 A 401\r"],["4TWD_A_377A402","4twd","377","Memantine (DB01043)","Dickeya chrysanthemi","CYS-LOOP LIGAND-GATED ION CHANNEL","NA",11,"LEU E 240;ALA D 244;ALA C 244;ALA B 244;ALA E 244;ALA A 244;SER B 247;SER E 247;SER A 247;SER C 247;SER D 247","377 A 402\r"]]