Ligand ID: 356

Drugbank ID:
Linagliptin
(DB08882)

Indication:
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.

LIST OF BINDING INTERFACES for query '356'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2RGU_A_356A901	2rgu	356	Linagliptin (DB08882)	Homo sapiens	DIPEPTIDYL PEPTIDASE 4	DPPIV_N Peptidase_S9	16	ARG A 125 GLU A 205 GLU A 206 PHE A 357 TYR A 547 TRP A 627 TRP A 629 SER A 630 TYR A 631 GLY A 632 VAL A 656 TYR A 662 TYR A 666 VAL A 711 HIS A 740 GLY A 741	356 A 901		Details
6Y0F_A_356A806	6y0f	356	Linagliptin (DB08882)	Homo sapiens	PROLYL ENDOPEPTIDASE FAP	DPPIV_N	17	ARG A 123 GLU A 203 GLU A 204 PHE A 350 TYR A 541 TRP A 621 TRP A 623 SER A 624 TYR A 625 GLY A 626 VAL A 650 TYR A 656 TYR A 660 ASN A 704 VAL A 705 HIS A 734 TYR A 745	356 A 806		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2RGU_A_356A901","2rgu","356","Linagliptin (DB08882)","Homo sapiens","DIPEPTIDYL PEPTIDASE 4","DPPIV_N;Peptidase_S9",16,"ARG A 125;GLU A 205;GLU A 206;PHE A 357;TYR A 547;TRP A 627;TRP A 629;SER A 630;TYR A 631;GLY A 632;VAL A 656;TYR A 662;TYR A 666;VAL A 711;HIS A 740;GLY A 741","356 A 901\r"],["6Y0F_A_356A806","6y0f","356","Linagliptin (DB08882)","Homo sapiens","PROLYL ENDOPEPTIDASE FAP","DPPIV_N",17,"ARG A 123;GLU A 203;GLU A 204;PHE A 350;TYR A 541;TRP A 621;TRP A 623;SER A 624;TYR A 625;GLY A 626;VAL A 650;TYR A 656;TYR A 660;ASN A 704;VAL A 705;HIS A 734;TYR A 745","356 A 806\r"]]