Ligand ID: 2K2

Drugbank ID:
Midostaurin
(DB06595)

Indication:
Midostaurin is an antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).

LIST OF BINDING INTERFACES for query '2K2'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4NCT_A_2K2A501	4nct	2K2	Midostaurin (DB06595)	Homo sapiens	DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A	Pkinase	21	ILE A 165 GLY A 166 LYS A 167 PHE A 170 VAL A 173 ALA A 186 LYS A 188 GLU A 203 VAL A 222 PHE A 238 GLU A 239 MET A 240 LEU A 241 SER A 242 ASN A 244 TYR A 246 GLU A 291 ASN A 292 LEU A 294 VAL A 306 ASP A 307	2K2 A 501		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4NCT_A_2K2A501","4nct","2K2","Midostaurin (DB06595)","Homo sapiens","DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A","Pkinase",21,"ILE A 165;GLY A 166;LYS A 167;PHE A 170;VAL A 173;ALA A 186;LYS A 188;GLU A 203;VAL A 222;PHE A 238;GLU A 239;MET A 240;LEU A 241;SER A 242;ASN A 244;TYR A 246;GLU A 291;ASN A 292;LEU A 294;VAL A 306;ASP A 307","2K2 A 501\r"]]