Ligand ID: 1C9

Drugbank ID:
Dacomitinib
(DB11963)

Indication:
Dacomitinib is a medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.

LIST OF BINDING INTERFACES for query '1C9'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4I24_A_1C9A9001	4i24	1C9	Dacomitinib (DB11963)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	PK_Tyr_Ser-Thr	21	LEU A 718 VAL A 726 ALA A 743 ILE A 744 LYS A 745 LEU A 788 ILE A 789 MET A 790 GLN A 791 LEU A 792 MET A 793 PRO A 794 PHE A 795 GLY A 796 CYS A 797 LEU A 799 ASP A 800 ARG A 841 LEU A 844 THR A 854 ASP A 855	1C9 A9001		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4I24_A_1C9A9001","4i24","1C9","Dacomitinib (DB11963)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","PK_Tyr_Ser-Thr",21,"LEU A 718;VAL A 726;ALA A 743;ILE A 744;LYS A 745;LEU A 788;ILE A 789;MET A 790;GLN A 791;LEU A 792;MET A 793;PRO A 794;PHE A 795;GLY A 796;CYS A 797;LEU A 799;ASP A 800;ARG A 841;LEU A 844;THR A 854;ASP A 855","1C9 A9001\r"]]