Ligand ID: 117

Drugbank ID:
Atorvastatin
(DB01076)

Indication:
Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.

LIST OF BINDING INTERFACES for query '117'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1HWK_A_117A2	1hwk	117	Atorvastatin (DB01076)	Homo sapiens	HMG-COA REDUCTASE	HMG-CoA_red	25	GLU B 559 GLY B 560 CYS B 561 LEU B 562 ALA B 564 SER B 565 ARG B 568 ARG A 590 SER A 661 VAL A 683 SER A 684 ASN A 686 CYS A 688 ASP A 690 LYS A 691 LYS A 692 LYS B 735 ALA B 751 HIS B 752 ASN B 755 SER B 852 LEU B 853 ALA B 856 LEU B 857 GLY B 860	117 A   2		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1HWK_A_117A2","1hwk","117","Atorvastatin (DB01076)","Homo sapiens","HMG-COA REDUCTASE","HMG-CoA_red",25,"GLU B 559;GLY B 560;CYS B 561;LEU B 562;ALA B 564;SER B 565;ARG B 568;ARG A 590;SER A 661;VAL A 683;SER A 684;ASN A 686;CYS A 688;ASP A 690;LYS A 691;LYS A 692;LYS B 735;ALA B 751;HIS B 752;ASN B 755;SER B 852;LEU B 853;ALA B 856;LEU B 857;GLY B 860","117 A 2\r"]]