Ligand ID: 0WM

Drugbank ID:
Afatinib
(DB08916)

Indication:
Afatinib is an antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy.

LIST OF BINDING INTERFACES for query '0WM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4G5J_A_0WMA1102	4g5j	0WM	Afatinib (DB08916)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	PK_Tyr_Ser-Thr	8	PHE A 795 TYR A 801 HIS A 805 ASN A 808 ILE A 809 TYR A 813 PRO A 848 HIS A 988	0WM A1102		Details
4G5J_A_0WMA1103	4g5j	0WM	Afatinib (DB08916)	Homo sapiens	EPIDERMAL GROWTH FACTOR RECEPTOR	PK_Tyr_Ser-Thr	7	ASP A 807 ASN A 808 GLU A 985 ARG A 986 MET A 987 HIS A 988 LEU A 989	0WM A1103		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4G5J_A_0WMA1102","4g5j","0WM","Afatinib (DB08916)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","PK_Tyr_Ser-Thr",8,"PHE A 795;TYR A 801;HIS A 805;ASN A 808;ILE A 809;TYR A 813;PRO A 848;HIS A 988","0WM A1102\r"],["4G5J_A_0WMA1103","4g5j","0WM","Afatinib (DB08916)","Homo sapiens","EPIDERMAL GROWTH FACTOR RECEPTOR","PK_Tyr_Ser-Thr",7,"ASP A 807;ASN A 808;GLU A 985;ARG A 986;MET A 987;HIS A 988;LEU A 989","0WM A1103\r"]]