Ligand ID: VIA

Drugbank ID:
Sildenafil
(DB00203)

Indication:
Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction.

LIST OF BINDING INTERFACES for query 'Sildenafil'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1TBF_A_VIAA501	1tbf	VIA	Sildenafil (DB00203)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE	PDEase_I	16	TYR A 612 HIS A 613 LEU A 725 LEU A 765 ALA A 767 ILE A 768 ALA A 779 VAL A 782 ALA A 783 PHE A 786 LEU A 804 ILE A 813 MET A 816 GLN A 817 PHE A 820 ILE A 824	VIA A 501		Details
1XOS_A_VIAA1	1xos	VIA	Sildenafil (DB00203)	Homo sapiens	CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B	PDEase_I	16	TYR A 233 HIS A 234 MET A 347 ASP A 392 LEU A 393 ASN A 395 TYR A 403 ILE A 410 MET A 411 PHE A 414 SER A 429 MET A 431 SER A 442 GLN A 443 PHE A 446 ILE A 450	VIA A   1		Details
3JWQ_A_VIAA901	3jwq	VIA	Sildenafil (DB00203)	Homo sapiens	CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA	PDEase_I	14	TYR A 612 HIS A 613 LEU A 725 LEU A 765 ALA A 767 ALA A 779 VAL A 782 PHE A 786 MET A 804 LEU A 813 LEU A 816 GLN A 817 PHE A 820 VAL A 824	VIA A 901		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1TBF_A_VIAA501","1tbf","VIA","Sildenafil (DB00203)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","PDEase_I",16,"TYR A 612;HIS A 613;LEU A 725;LEU A 765;ALA A 767;ILE A 768;ALA A 779;VAL A 782;ALA A 783;PHE A 786;LEU A 804;ILE A 813;MET A 816;GLN A 817;PHE A 820;ILE A 824","VIA A 501\r"],["1XOS_A_VIAA1","1xos","VIA","Sildenafil (DB00203)","Homo sapiens","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","PDEase_I",16,"TYR A 233;HIS A 234;MET A 347;ASP A 392;LEU A 393;ASN A 395;TYR A 403;ILE A 410;MET A 411;PHE A 414;SER A 429;MET A 431;SER A 442;GLN A 443;PHE A 446;ILE A 450","VIA A 1\r"],["3JWQ_A_VIAA901","3jwq","VIA","Sildenafil (DB00203)","Homo sapiens","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","PDEase_I",14,"TYR A 612;HIS A 613;LEU A 725;LEU A 765;ALA A 767;ALA A 779;VAL A 782;PHE A 786;MET A 804;LEU A 813;LEU A 816;GLN A 817;PHE A 820;VAL A 824","VIA A 901\r"]]