Ligand ID: 6GY

Drugbank ID:
Brigatinib
(DB12267)

Indication:
Brigatinib is an anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.


LIST OF BINDING INTERFACES for query 'DB12267'
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
6MX8_A_6GYA15006mx8 6GYBrigatinib
(DB12267) 		Homo sapiens ALK TYROSINE KINASE RECEPTOR PK_Tyr_Ser-Thr 19LEU A1122
GLY A1123
HIS A1124
VAL A1130
ALA A1148
LYS A1150
LEU A1196
GLU A1197
LEU A1198
MET A1199
ALA A1200
GLY A1202
ASP A1203
GLU A1210
ARG A1253
ASN A1254
LEU A1256
GLY A1269
ASP A1270
6GY A1500
7AEM_A_6GYA11017aem 6GYBrigatinib
(DB12267) 		Homo sapiens EPIDERMAL GROWTH FACTOR RECEPTOR PK_Tyr_Ser-Thr 19LEU A 718
GLY A 719
PHE A 723
VAL A 726
ALA A 743
LYS A 745
THR A 790
GLN A 791
LEU A 792
MET A 793
PRO A 794
GLY A 796
CYS A 797
GLU A 804
ARG A 841
ASN A 842
LEU A 844
THR A 854
ASP A 855
6GY A1101
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details