Ligand ID: F5O

Drugbank ID:
Elagolix
(DB11979)

Indication:
Elagolix is a gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.

LIST OF BINDING INTERFACES for query 'DB11979'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
7BR3_A_F5OA1211	7br3	F5O	Elagolix (DB11979)	Homo sapiens; pyrococcus abyssi (strain ge5 / orsay)	GONADOTROPIN-RELEASING HORMONE RECEPTOR,GLGA GLYCOGEN SYNTHASE,GONADOTROPIN-RELEASING HORMONE RECEPTOR	7tm_1 Glycos_transf_1	27	ILE A  21 PRO A  22 LEU A  23 MET A  24 GLN A  25 GLY A  26 ASN A  27 ASP A  98 ASN A 102 ILE A 103 LYS A 121 MET A 125 ASN A 212 THR A 215 PHE A 216 LEU A 219 TYR A 283 TYR A 284 LEU A 286 GLY A 287 TYR A 290 MET A 296 LEU A 297 VAL A 304 ASN A 305 PHE A 308 PHE A 309	F5O A1211		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["7BR3_A_F5OA1211","7br3","F5O","Elagolix (DB11979)","Homo sapiens;pyrococcus abyssi (strain ge5 \/ orsay)","GONADOTROPIN-RELEASING HORMONE RECEPTOR,GLGA GLYCOGEN SYNTHASE,GONADOTROPIN-RELEASING HORMONE RECEPTOR","7tm_1;Glycos_transf_1",27,"ILE A 21;PRO A 22;LEU A 23;MET A 24;GLN A 25;GLY A 26;ASN A 27;ASP A 98;ASN A 102;ILE A 103;LYS A 121;MET A 125;ASN A 212;THR A 215;PHE A 216;LEU A 219;TYR A 283;TYR A 284;LEU A 286;GLY A 287;TYR A 290;MET A 296;LEU A 297;VAL A 304;ASN A 305;PHE A 308;PHE A 309","F5O A1211\r"]]