Ligand ID: NRK

Drugbank ID:
Lemborexant
(DB11951)


Indication:
Lemborexant is a dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia.


LIST OF BINDING INTERFACES for query 'DB11951'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
6TOT_A_NRKA4016tot NRKLemborexant
(DB11951)
Homo sapiens OREXIN RECEPTOR TYPE 1 7tm_1 21CYS A  99
ALA A 102
SER A 103
VAL A 106
ASP A 107
TRP A 112
ILE A 122
PRO A 123
GLN A 126
ALA A 127
VAL A 130
GLN A 179
GLU A 204
PHE A 219
TYR A 311
ILE A 314
SER A 315
ASN A 318
HIS A 344
VAL A 347
TYR A 348
NRK A 401
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details