Ligand ID: TKT

Drugbank ID:
Tropisetron
(DB11699)

Indication:
Tropisetron is a 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting.

LIST OF BINDING INTERFACES for query 'DB11699'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2WNC_A_TKTA300	2wnc	TKT	Tropisetron (DB11699)	Aplysia californica	SOLUBLE ACETYLCHOLINE RECEPTOR	Neur_chan_LBD	12	THR E  36 TYR E  55 GLN E  57 TYR A  93 MET E 116 ILE E 118 SER A 146 TRP A 147 TYR A 188 CYS A 190 CYS A 191 TYR A 195	TKT A 300		Details
6HIS_A_TKTA508	6his	TKT	Tropisetron (DB11699)	Mus musculus	5-HYDROXYTRYPTAMINE RECEPTOR 3A	Neur_chan_LBD Neur_chan_memb	12	ASP A  42 ILE A  44 TRP A  63 ARG A  65 ASN B 101 TYR A 126 THR B 154 SER B 155 TRP B 156 ARG A 169 ILE B 201 TYR B 207	TKT A 508		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2WNC_A_TKTA300","2wnc","TKT","Tropisetron (DB11699)","Aplysia californica","SOLUBLE ACETYLCHOLINE RECEPTOR","Neur_chan_LBD",12,"THR E 36;TYR E 55;GLN E 57;TYR A 93;MET E 116;ILE E 118;SER A 146;TRP A 147;TYR A 188;CYS A 190;CYS A 191;TYR A 195","TKT A 300\r"],["6HIS_A_TKTA508","6his","TKT","Tropisetron (DB11699)","Mus musculus","5-HYDROXYTRYPTAMINE RECEPTOR 3A","Neur_chan_LBD;Neur_chan_memb",12,"ASP A 42;ILE A 44;TRP A 63;ARG A 65;ASN B 101;TYR A 126;THR B 154;SER B 155;TRP B 156;ARG A 169;ILE B 201;TYR B 207","TKT A 508\r"]]