Ligand ID: EMH

Drugbank ID:
Alectinib
(DB11363)

Indication:
Alectinib is a kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.

LIST OF BINDING INTERFACES for query 'DB11363'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3AOX_A_EMHA901	3aox	EMH	Alectinib (DB11363)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PK_Tyr_Ser-Thr	17	ARG A1120 LEU A1122 GLY A1123 VAL A1130 GLU A1132 ALA A1148 LYS A1150 VAL A1180 LEU A1196 GLU A1197 LEU A1198 MET A1199 ALA A1200 GLY A1202 ASP A1203 LEU A1256 GLY A1269	EMH A 901		Details
5XV7_A_EMHA705	5xv7	EMH	Alectinib (DB11363)	Homo sapiens	SERINE-ARGININE (SR) PROTEIN KINASE 1	Pkinase	19	ARG A  84 LEU A  86 GLY A  87 VAL A  94 ALA A 107 VAL A 145 PHE A 165 GLU A 166 VAL A 167 LEU A 168 GLY A 169 HIS A 170 LYS A 174 LEU A 220 VAL A 223 TYR A 227 LEU A 231 ALA A 496 ASP A 497	EMH A 705		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3AOX_A_EMHA901","3aox","EMH","Alectinib (DB11363)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PK_Tyr_Ser-Thr",17,"ARG A1120;LEU A1122;GLY A1123;VAL A1130;GLU A1132;ALA A1148;LYS A1150;VAL A1180;LEU A1196;GLU A1197;LEU A1198;MET A1199;ALA A1200;GLY A1202;ASP A1203;LEU A1256;GLY A1269","EMH A 901\r"],["5XV7_A_EMHA705","5xv7","EMH","Alectinib (DB11363)","Homo sapiens","SERINE-ARGININE (SR) PROTEIN KINASE 1","Pkinase",19,"ARG A 84;LEU A 86;GLY A 87;VAL A 94;ALA A 107;VAL A 145;PHE A 165;GLU A 166;VAL A 167;LEU A 168;GLY A 169;HIS A 170;LYS A 174;LEU A 220;VAL A 223;TYR A 227;LEU A 231;ALA A 496;ASP A 497","EMH A 705\r"]]