Results: Ligand

Ligand ID: THH

Drugbank ID:
Levomefolic acid
(DB11256)

Indication:
Levomefolic acid is a folate supplement used to prevent neural tube defects in pregnancy or folate deficiency.

LIST OF BINDING INTERFACES for query 'DB11256'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1WSV_A_THHA3001	1wsv	THH	Levomefolic acid (DB11256)	Homo sapiens	AMINOMETHYLTRANSFERASE	GCV_T GCV_T_C	19	MET A 56 THR A 87 LEU A 88 ASP A 101 LEU A 102 ILE A 103 VAL A 115 SER A 116 ASN A 117 PHE A 176 MET A 177 CYS A 195 GLY A 196 TYR A 197 GLU A 204 ARG A 233 LEU A 242 TRP A 262 TYR A 371	THH A3001
3DCJ_A_THHA401	3dcj	THH	Levomefolic acid (DB11256)	Mycobacterium tuberculosis	PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN	Formyl_trans_N	22	PRO B 8 PRO B 9 ALA B 11 SER A 95 PHE A 98 MET A 99 ARG A 100 ILE A 101 LEU A 102 LEU A 107 ASN A 116 HIS A 118 PRO A 119 GLY A 127 THR A 128 HIS A 147 VAL A 149 ASP A 150 ALA A 151 GLY A 152 THR A 153 ASP A 154	THH A 401
3K13_A_THHA642	3k13	THH	Levomefolic acid (DB11256)	Bacteroides thetaiotaomicron	5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE	Pterin_bind	17	GLU A 358 ASN A 361 GLY A 364 SER A 365 ARG A 366 ASP A 396 ASP A 431 ASN A 452 VAL A 478 ASP A 519 GLY A 558 SER A 560 ASN A 561 PHE A 564 ARG A 567 ARG A 573 ILE A 593	THH A 642
6SK4_A_THHA901	6sk4	THH	Levomefolic acid (DB11256)	Desulfitobacterium hafniense y51	METHYLCORRINOID:TETRAHYDROFOLATE METHYLTRANSFERASE	MtrH	19	SER A 32 TYR A 35 ARG A 36 ASP A 75 LEU A 77 ASP A 102 ASN A 129 VAL A 152 LEU A 154 ASP A 194 ALA A 224 SER A 226 ASN A 227 TYR A 230 LEU A 231 ARG A 236 LEU A 263 GLY A 265 PRO A 266	THH A 901
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1WSV_A_THHA3001","1wsv","THH","Levomefolic acid (DB11256)","Homo sapiens","AMINOMETHYLTRANSFERASE","GCV_T;GCV_T_C",19,"MET A  56;THR A  87;LEU A  88;ASP A 101;LEU A 102;ILE A 103;VAL A 115;SER A 116;ASN A 117;PHE A 176;MET A 177;CYS A 195;GLY A 196;TYR A 197;GLU A 204;ARG A 233;LEU A 242;TRP A 262;TYR A 371","THH A3001\r"],["3DCJ_A_THHA401","3dcj","THH","Levomefolic acid (DB11256)","Mycobacterium tuberculosis","PROBABLE 5'-PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE PURN","Formyl_trans_N",22,"PRO B   8;PRO B   9;ALA B  11;SER A  95;PHE A  98;MET A  99;ARG A 100;ILE A 101;LEU A 102;LEU A 107;ASN A 116;HIS A 118;PRO A 119;GLY A 127;THR A 128;HIS A 147;VAL A 149;ASP A 150;ALA A 151;GLY A 152;THR A 153;ASP A 154","THH A 401\r"],["3K13_A_THHA642","3k13","THH","Levomefolic acid (DB11256)","Bacteroides thetaiotaomicron","5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE","Pterin_bind",17,"GLU A 358;ASN A 361;GLY A 364;SER A 365;ARG A 366;ASP A 396;ASP A 431;ASN A 452;VAL A 478;ASP A 519;GLY A 558;SER A 560;ASN A 561;PHE A 564;ARG A 567;ARG A 573;ILE A 593","THH A 642\r"],["6SK4_A_THHA901","6sk4","THH","Levomefolic acid (DB11256)","Desulfitobacterium hafniense y51","METHYLCORRINOID:TETRAHYDROFOLATE METHYLTRANSFERASE","MtrH",19,"SER A  32;TYR A  35;ARG A  36;ASP A  75;LEU A  77;ASP A 102;ASN A 129;VAL A 152;LEU A 154;ASP A 194;ALA A 224;SER A 226;ASN A 227;TYR A 230;LEU A 231;ARG A 236;LEU A 263;GLY A 265;PRO A 266","THH A 901\r"]]