Ligand ID: PAC

Drugbank ID:
Phenylacetic acid
(DB09269)

Indication:
Phenylacetic acid is an agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle.

LIST OF BINDING INTERFACES for query 'DB09269'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1FXH_B_PACB1001	1fxh	PAC	Phenylacetic acid (DB09269)	Escherichia coli	PENICILLIN ACYLASE	NA	11	SER B   1 PRO B  22 GLN B  23 PHE B  24 SER B  67 THR B  68 ALA B  69 PHE B  71 MET A 142 PHE A 146 ILE B 177	PAC B1001		Details
2INE_A_PACA317	2ine	PAC	Phenylacetic acid (DB09269)	Homo sapiens	ALDOSE REDUCTASE	Aldo_ket_red	7	TRP A  20 VAL A  47 TYR A  48 HIS A 110 TRP A 111 PHE A 122 TRP A 219	PAC A 317		Details
2Y4N_B_PACB503	2y4n	PAC	Phenylacetic acid (DB09269)	Burkholderia cenocepacia	PHENYLACETATE-COENZYME A LIGASE	AMP-binding AMP-binding_C_2	6	SER B  93 SER B  94 GLY B 137 PHE B 141 GLY B 421 LYS B 422	PAC B 503		Details
3IXL_A_PACA5000	3ixl	PAC	Phenylacetic acid (DB09269)	Bordetella bronchiseptica	ARYLMALONATE DECARBOXYLASE	Amdase	13	PRO A  14 VAL A  43 MET A  73 CYS A  74 THR A  75 SER A  76 MET A 104 TYR A 126 VAL A 156 MET A 159 SER A 188 GLY A 189 GLY A 190	PAC A5000		Details
4YFB_C_PACC601	4yfb	PAC	Phenylacetic acid (DB09269)	Acidovorax sp. mr-s7	PROTEIN RELATED TO PENICILLIN ACYLASE	NA	14	SER C   1 PRO C  22 HIS C  23 TRP C  24 PHE C  32 PHE C  50 GLN C  57 ILE C  58 HIS C  68 THR C  69 VAL C  70 TRP C 165 TRP C 189 VAL C 190	PAC C 601		Details
6A0M_A_PACA402	6a0m	PAC	Phenylacetic acid (DB09269)	Amycolatopsis orientalis	4-HYDROXYMANDELATE OXIDASE	FMN_dh	9	PHE A  24 ALA A  79 TYR A  80 LEU A 108 PHE A 128 MET A 160 ARG A 163 HIS A 252 ARG A 255	PAC A 402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1FXH_B_PACB1001","1fxh","PAC","Phenylacetic acid (DB09269)","Escherichia coli","PENICILLIN ACYLASE","NA",11,"SER B 1;PRO B 22;GLN B 23;PHE B 24;SER B 67;THR B 68;ALA B 69;PHE B 71;MET A 142;PHE A 146;ILE B 177","PAC B1001\r"],["2INE_A_PACA317","2ine","PAC","Phenylacetic acid (DB09269)","Homo sapiens","ALDOSE REDUCTASE","Aldo_ket_red",7,"TRP A 20;VAL A 47;TYR A 48;HIS A 110;TRP A 111;PHE A 122;TRP A 219","PAC A 317\r"],["2Y4N_B_PACB503","2y4n","PAC","Phenylacetic acid (DB09269)","Burkholderia cenocepacia","PHENYLACETATE-COENZYME A LIGASE","AMP-binding;AMP-binding_C_2",6,"SER B 93;SER B 94;GLY B 137;PHE B 141;GLY B 421;LYS B 422","PAC B 503\r"],["3IXL_A_PACA5000","3ixl","PAC","Phenylacetic acid (DB09269)","Bordetella bronchiseptica","ARYLMALONATE DECARBOXYLASE","Amdase",13,"PRO A 14;VAL A 43;MET A 73;CYS A 74;THR A 75;SER A 76;MET A 104;TYR A 126;VAL A 156;MET A 159;SER A 188;GLY A 189;GLY A 190","PAC A5000\r"],["4YFB_C_PACC601","4yfb","PAC","Phenylacetic acid (DB09269)","Acidovorax sp. mr-s7","PROTEIN RELATED TO PENICILLIN ACYLASE","NA",14,"SER C 1;PRO C 22;HIS C 23;TRP C 24;PHE C 32;PHE C 50;GLN C 57;ILE C 58;HIS C 68;THR C 69;VAL C 70;TRP C 165;TRP C 189;VAL C 190","PAC C 601\r"],["6A0M_A_PACA402","6a0m","PAC","Phenylacetic acid (DB09269)","Amycolatopsis orientalis","4-HYDROXYMANDELATE OXIDASE","FMN_dh",9,"PHE A 24;ALA A 79;TYR A 80;LEU A 108;PHE A 128;MET A 160;ARG A 163;HIS A 252;ARG A 255","PAC A 402\r"]]