Ligand ID: 4MK

Drugbank ID:
Ceritinib
(DB09063)

Indication:
Ceritinib is an antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.

LIST OF BINDING INTERFACES for query 'DB09063'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4MKC_A_4MKA1503	4mkc	4MK	Ceritinib (DB09063)	Homo sapiens	ALK TYROSINE KINASE RECEPTOR	PK_Tyr_Ser-Thr	22	LEU A1122 GLY A1123 HIS A1124 GLY A1125 VAL A1130 GLU A1132 ALA A1148 LYS A1150 LEU A1196 GLU A1197 LEU A1198 MET A1199 ALA A1200 GLY A1202 ASP A1203 SER A1206 GLU A1210 ARG A1253 ASN A1254 LEU A1256 GLY A1269 ASP A1270	4MK A1503		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4MKC_A_4MKA1503","4mkc","4MK","Ceritinib (DB09063)","Homo sapiens","ALK TYROSINE KINASE RECEPTOR","PK_Tyr_Ser-Thr",22,"LEU A1122;GLY A1123;HIS A1124;GLY A1125;VAL A1130;GLU A1132;ALA A1148;LYS A1150;LEU A1196;GLU A1197;LEU A1198;MET A1199;ALA A1200;GLY A1202;ASP A1203;SER A1206;GLU A1210;ARG A1253;ASN A1254;LEU A1256;GLY A1269;ASP A1270","4MK A1503\r"]]