Results: Ligand

Ligand ID: SUV

Drugbank ID:
Suvorexant
(DB09034)

Indication:
Suvorexant is a orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance.

LIST OF BINDING INTERFACES for query 'DB09034'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4S0V_A_SUVA2001	4s0v	SUV	Suvorexant (DB09034)	Homo sapiens; pyrococcus abyssi ge5	HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE	7tm_1 Glycos_transf_1	20	CYS A 107 ALA A 110 THR A 111 VAL A 114 TRP A 120 ILE A 130 PRO A 131 GLN A 134 THR A 135 VAL A 138 GLN A 187 GLU A 212 HIS A 224 PHE A 227 TYR A 317 ILE A 320 ASN A 324 HIS A 350 VAL A 353 TYR A 354	SUV A2001
4ZJ8_A_SUVA2001	4zj8	SUV	Suvorexant (DB09034)	Homo sapiens; pyrococcus abyssi (strain ge5 / orsay)	HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE	7tm_1 Glycos_transf_1	21	CYS A 99 ALA A 102 SER A 103 VAL A 106 TRP A 112 ILE A 122 PRO A 123 GLN A 126 ALA A 127 VAL A 130 GLN A 179 MET A 183 GLU A 204 HIS A 216 PHE A 219 TYR A 311 ILE A 314 ASN A 318 HIS A 344 VAL A 347 TYR A 348	SUV A2001
6TO7_A_SUVA401	6to7	SUV	Suvorexant (DB09034)	Homo sapiens	OREXIN RECEPTOR TYPE 1	7tm_1	20	CYS A 99 ALA A 102 SER A 103 VAL A 106 TRP A 112 ILE A 122 PRO A 123 GLN A 126 ALA A 127 VAL A 130 GLN A 179 GLU A 204 HIS A 216 PHE A 219 TYR A 311 ILE A 314 ASN A 318 HIS A 344 VAL A 347 TYR A 348	SUV A 401
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4S0V_A_SUVA2001","4s0v","SUV","Suvorexant (DB09034)","Homo sapiens;pyrococcus abyssi ge5","HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE","7tm_1;Glycos_transf_1",20,"CYS A 107;ALA A 110;THR A 111;VAL A 114;TRP A 120;ILE A 130;PRO A 131;GLN A 134;THR A 135;VAL A 138;GLN A 187;GLU A 212;HIS A 224;PHE A 227;TYR A 317;ILE A 320;ASN A 324;HIS A 350;VAL A 353;TYR A 354","SUV A2001\r"],["4ZJ8_A_SUVA2001","4zj8","SUV","Suvorexant (DB09034)","Homo sapiens;pyrococcus abyssi (strain ge5 \/ orsay)","HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE","7tm_1;Glycos_transf_1",21,"CYS A  99;ALA A 102;SER A 103;VAL A 106;TRP A 112;ILE A 122;PRO A 123;GLN A 126;ALA A 127;VAL A 130;GLN A 179;MET A 183;GLU A 204;HIS A 216;PHE A 219;TYR A 311;ILE A 314;ASN A 318;HIS A 344;VAL A 347;TYR A 348","SUV A2001\r"],["6TO7_A_SUVA401","6to7","SUV","Suvorexant (DB09034)","Homo sapiens","OREXIN RECEPTOR TYPE 1","7tm_1",20,"CYS A  99;ALA A 102;SER A 103;VAL A 106;TRP A 112;ILE A 122;PRO A 123;GLN A 126;ALA A 127;VAL A 130;GLN A 179;GLU A 204;HIS A 216;PHE A 219;TYR A 311;ILE A 314;ASN A 318;HIS A 344;VAL A 347;TYR A 348","SUV A 401\r"]]