Ligand ID: VX7

Drugbank ID:
Ivacaftor
(DB08820)

Indication:
Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication.

LIST OF BINDING INTERFACES for query 'DB08820'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6O2P_A_VX7A1512	6o2p	VX7	Ivacaftor (DB08820)	Homo sapiens	CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR	ABC_membrane ABC_tran CFTR_R	10	LEU A 233 PHE A 236 TYR A 304 PHE A 305 SER A 308 ALA A 309 PHE A 312 GLY A 930 PHE A 931 PHE A 932	VX7 A1512		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6O2P_A_VX7A1512","6o2p","VX7","Ivacaftor (DB08820)","Homo sapiens","CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR","ABC_membrane;ABC_tran;CFTR_R",10,"LEU A 233;PHE A 236;TYR A 304;PHE A 305;SER A 308;ALA A 309;PHE A 312;GLY A 930;PHE A 931;PHE A 932","VX7 A1512\r"]]