Ligand ID: GG2

Drugbank ID:
Apixaban
(DB06605)

Indication:
Apixaban is an anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.

LIST OF BINDING INTERFACES for query 'DB06605'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2P16_A_GG2A298	2p16	GG2	Apixaban (DB06605)	Homo sapiens	COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR)	Trypsin	22	LYS A  96 GLU A  97 THR A  98 TYR A  99 ARG A 143 GLU A 146 PHE A 174 ASP A 189 ALA A 190 CYS A 191 GLN A 192 SER A 195 VAL A 213 SER A 214 TRP A 215 GLY A 216 GLU A 217 GLY A 218 CYS A 220 GLY A 226 ILE A 227 TYR A 228	GG2 A 298		Details
6W70_A_GG2A303	6w70	GG2	Apixaban (DB06605)	Synthetic construct	DE NOVO DESIGNED ABLE	NA	29	TYR A   6 ALA A   9 ALA A  10 GLY A  13 GLN A  14 ALA A  16 VAL A  17 PHE A  20 TYR A  46 HIS A  49 LEU A  53 ILE A  56 MET A  72 PHE A  75 THR A  78 PHE A  79 GLY A  82 LYS A  83 PHE A  86 ALA C  88 TYR C 104 LEU A 108 VAL A 111 THR A 112 GLY A 115 GLU A 116 ALA A 119 ILE A 122 ALA A 123	GG2 A 303		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2P16_A_GG2A298","2p16","GG2","Apixaban (DB06605)","Homo sapiens","COAGULATION FACTOR X (EC 3.4.21.6) (STUART FACTOR) (STUART-PROWER FACTOR)","Trypsin",22,"LYS A 96;GLU A 97;THR A 98;TYR A 99;ARG A 143;GLU A 146;PHE A 174;ASP A 189;ALA A 190;CYS A 191;GLN A 192;SER A 195;VAL A 213;SER A 214;TRP A 215;GLY A 216;GLU A 217;GLY A 218;CYS A 220;GLY A 226;ILE A 227;TYR A 228","GG2 A 298\r"],["6W70_A_GG2A303","6w70","GG2","Apixaban (DB06605)","Synthetic construct","DE NOVO DESIGNED ABLE","NA",29,"TYR A 6;ALA A 9;ALA A 10;GLY A 13;GLN A 14;ALA A 16;VAL A 17;PHE A 20;TYR A 46;HIS A 49;LEU A 53;ILE A 56;MET A 72;PHE A 75;THR A 78;PHE A 79;GLY A 82;LYS A 83;PHE A 86;ALA C 88;TYR C 104;LEU A 108;VAL A 111;THR A 112;GLY A 115;GLU A 116;ALA A 119;ILE A 122;ALA A 123","GG2 A 303\r"]]