Ligand ID: AWY

Drugbank ID:
Agomelatine
(DB06594)

Indication:
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine...


LIST OF BINDING INTERFACES for query 'DB06594'
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
5Q1S_A_AWYA11035q1s AWYAgomelatine
(DB06594) 		Homo sapiens DNA CROSS-LINK REPAIR 1A PROTEIN DRMBL 13LYS A 831
VAL A1004
GLN A1005
LYS A1008
PRO A1009
GLN A1010
LYS A1011
ILE A1012
PHE A1031
TRP A1034
LYS A1035
ALA A1038
TYR A1040
AWY A1103
6ME5_A_AWYA12016me5 AWYAgomelatine
(DB06594) 		Homo sapiens;
pyrococcus abyssi ge5 		CHIMERA PROTEIN OF MELATONIN RECEPTOR TYPE 1A AND GLGA GLYCOGEN SYNTHASE 7tm_1
Glycos_transf_1 		16ALA A 104
MET A 107
GLY A 108
VAL A 111
ILE A 112
VAL A 159
ASN A 162
LEU A 168
THR A 178
PHE A 179
GLN A 181
THR A 188
VAL A 191
VAL A 192
LEU A 254
ASN A 255
AWY A1201
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details