Ligand ID: 65B

Drugbank ID:
Etravirine
(DB06414)

Indication:
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.

LIST OF BINDING INTERFACES for query 'DB06414'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3MEC_A_65BA561	3mec	65B	Etravirine (DB06414)	Hiv-1 m:b_hxb2r	P51 REVERSE TRANSCRIPTASE; P66 REVERSE TRANSCRIPTASE	RNase_H RVT_1 RVT_connect RVT_thumb	20	PRO A  95 LEU A 100 LYS A 101 LYS A 102 LYS A 103 VAL A 106 VAL A 108 GLU B 138 VAL A 179 TYR A 181 TYR A 188 VAL A 189 GLY A 190 PRO A 225 PHE A 227 TRP A 229 LEU A 234 HIS A 235 PRO A 236 TYR A 318	65B A 561		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3MEC_A_65BA561","3mec","65B","Etravirine (DB06414)","Hiv-1 m:b_hxb2r","P51 REVERSE TRANSCRIPTASE;P66 REVERSE TRANSCRIPTASE","RNase_H;RVT_1;RVT_connect;RVT_thumb",20,"PRO A 95;LEU A 100;LYS A 101;LYS A 102;LYS A 103;VAL A 106;VAL A 108;GLU B 138;VAL A 179;TYR A 181;TYR A 188;VAL A 189;GLY A 190;PRO A 225;PHE A 227;TRP A 229;LEU A 234;HIS A 235;PRO A 236;TYR A 318","65B A 561\r"]]