Ligand ID: ESL

Drugbank ID:
Estriol
(DB04573)

Indication:
Estriol is a weak estrogen used to treat vaginal dryness and estrogen deficiency conditions, such as vaginitis and vulvar itching.

LIST OF BINDING INTERFACES for query 'DB04573'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1X8V_A_ESLA471	1x8v	ESL	Estriol (DB04573)	Mycobacterium tuberculosis	CYTOCHROME P450 51	p450	15	GLN A  72 TYR A  76 PHE A  78 MET A  79 PHE A  83 ARG A  96 HIS A 101 SER A 252 PHE A 255 ALA A 256 HIS A 259 LEU A 321 ILE A 323 MET A 433 VAL A 434	ESL A 471		Details
1X8V_A_ESLA472	1x8v	ESL	Estriol (DB04573)	Mycobacterium tuberculosis	CYTOCHROME P450 51	p450	8	MET A  99 LEU A 100 MET A 225 VAL A 228 LEU A 229 ARG A 240 PHE A 241 MET A 249	ESL A 472		Details
3Q95_A_ESLA700	3q95	ESL	Estriol (DB04573)	Homo sapiens; synthetic construct	ESTROGEN RECEPTOR	Hormone_recep	17	MET A 343 LEU A 346 LEU A 349 ALA A 350 GLU A 353 LEU A 384 LEU A 387 MET A 388 LEU A 391 ARG A 394 PHE A 404 MET A 421 ILE A 424 LEU A 428 GLY A 521 HIS A 524 LEU A 525	ESL A 700		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1X8V_A_ESLA471","1x8v","ESL","Estriol (DB04573)","Mycobacterium tuberculosis","CYTOCHROME P450 51","p450",15,"GLN A 72;TYR A 76;PHE A 78;MET A 79;PHE A 83;ARG A 96;HIS A 101;SER A 252;PHE A 255;ALA A 256;HIS A 259;LEU A 321;ILE A 323;MET A 433;VAL A 434","ESL A 471\r"],["1X8V_A_ESLA472","1x8v","ESL","Estriol (DB04573)","Mycobacterium tuberculosis","CYTOCHROME P450 51","p450",8,"MET A 99;LEU A 100;MET A 225;VAL A 228;LEU A 229;ARG A 240;PHE A 241;MET A 249","ESL A 472\r"],["3Q95_A_ESLA700","3q95","ESL","Estriol (DB04573)","Homo sapiens;synthetic construct","ESTROGEN RECEPTOR","Hormone_recep",17,"MET A 343;LEU A 346;LEU A 349;ALA A 350;GLU A 353;LEU A 384;LEU A 387;MET A 388;LEU A 391;ARG A 394;PHE A 404;MET A 421;ILE A 424;LEU A 428;GLY A 521;HIS A 524;LEU A 525","ESL A 700\r"]]